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@article{58690,
   author = {Hruška, Pavel and Kučera, Jan and Kuruczová, Daniela and Buzga, Marek and Pekař, Matej and Holeczy, Pavol and Potěšil, David and Zdráhal, Zbyněk and Dobrovolná, Julie},
   article_location = {UNITED STATES},
   article_number = {5},
   doi = {http://dx.doi.org/10.1152/ajpendo.00153.2023},
   keywords = {obesity; proteomics; subcutaneous adipose tissue; type 2 diabetes; visceral adipose tissue},
   language = {eng},
   issn = {0193-1849},
   journal = {AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM},
   title = {Unraveling adipose tissue proteomic landscapes in severe obesity: insights into metabolic complications and potential biomarkers},
   url = {https://journals.physiology.org/doi/full/10.1152/ajpendo.00153.2023},
   volume = {325},
   year = {2023}
}

TY  - JOUR
ID  - 58690
AU  - Hruška, Pavel - Kučera, Jan - Kuruczová, Daniela - Buzga, Marek - Pekař, Matej - Holeczy, Pavol - Potěšil, David - Zdráhal, Zbyněk - Dobrovolná, Julie
PY  - 2023
TI  - Unraveling adipose tissue proteomic landscapes in severe obesity: insights into metabolic complications and potential biomarkers
JF  - AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
VL  - 325
IS  - 5
SP  - "E562"-"E580"
EP  - "E562"-"E580"
PB  - AMER PHYSIOLOGICAL SOC
SN  - 0193-1849
KW  - obesity
KW  - proteomics
KW  - subcutaneous adipose tissue
KW  - type 2 diabetes
KW  - visceral adipose tissue
UR  - https://journals.physiology.org/doi/full/10.1152/ajpendo.00153.2023
N2  - amp; NOTEWORTHY This study provides insights into distinct proteomic profiles of subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), and serum in patients with severe obesity and their associations with clinical traits and body composition. It underscores SAT's crucial role in obesity development and related complications, such as insulin resistance (IR) and type 2 diabetes (T2D). Our findings emphasize the importance of understanding the SAT and VAT balance in energy homeostasis, proteostasis, and the potential role of SAT capacity in the development of metabolic disorders.
ER  - 

HRUŠKA, Pavel, Jan KUČERA, Daniela KURUCZOVÁ, Marek BUZGA, Matej PEKAŘ, Pavol HOLECZY, David POTĚŠIL, Zbyněk ZDRÁHAL a Julie DOBROVOLNÁ. Unraveling adipose tissue proteomic landscapes in severe obesity: insights into metabolic complications and potential biomarkers. \textit{AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM}. UNITED STATES: AMER PHYSIOLOGICAL SOC, 2023, roč.~325, č.~5, s.~''E562''-''E580'', 19 s. ISSN~0193-1849. Dostupné z: https://dx.doi.org/10.1152/ajpendo.00153.2023.