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@proceedings{54131,
author = {Demo, Gabriel and Hassan, Ahmed Adel I. H. and Hiriyur Nagaraj, Pradeep and Veselá, Ludmila and Zafar, Hassan and Slámová, Lucie and Brabencová, Sylva},
booktitle = {Czech Chemical Society Symposium Series - Annual meeting of the National Institute of Virology and Bacteriology (NIVB)},
keywords = {mRNA; RNAP},
language = {eng},
title = {THE CLOSE INTERPLAY OF TWO GENE EXPRESSION MACHINERIES},
url = {http://www.ccsss.cz/index.php/ccsss/issue/view/37/67},
year = {2022}
}
TY - CONF
ID - 54131
AU - Demo, Gabriel - Hassan, Ahmed Adel I. H. - Hiriyur Nagaraj, Pradeep - Veselá, Ludmila - Zafar, Hassan - Slámová, Lucie - Brabencová, Sylva
PY - 2022
TI - THE CLOSE INTERPLAY OF TWO GENE EXPRESSION MACHINERIES
KW - mRNA
KW - RNAP
UR - http://www.ccsss.cz/index.php/ccsss/issue/view/37/67
N2 - In Bacteria, the transcribed messenger RNA (mRNA) can be directly attached to the first translating ribosome by creating a physical interaction between the ribosome and RNA polymerase (RNAP)1. The lead ribosome, in this transcription-translation complex, regulates the progression of transcription and protects the transcribed mRNA from premature transcription termination or mRNA degradation2. In the coupled system of transcription-translation the lead ribosome closely trails the RNAP, with rates of translation matching the transcription to support the efficient gene expression2.The direct interactions between RNAP and the translational machinery allow them to co-localize in bacterial cell and maintain the genome stability.
ER -
DEMO, Gabriel, Ahmed Adel I. H. HASSAN, Pradeep HIRIYUR NAGARAJ, Ludmila VESELÁ, Hassan ZAFAR, Lucie SLÁMOVÁ a Sylva BRABENCOVÁ. THE CLOSE INTERPLAY OF TWO GENE EXPRESSION MACHINERIES. In \textit{Czech Chemical Society Symposium Series - Annual meeting of the National Institute of Virology and Bacteriology (NIVB)}. 2022. ISSN~2336-7202.
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