2022
THE CLOSE INTERPLAY OF TWO GENE EXPRESSION MACHINERIES
DEMO, Gabriel; Ahmed Adel I. H. HASSAN; Pradeep HIRIYUR NAGARAJ; Ludmila VESELÁ; Hassan ZAFAR et. al.Basic information
Original name
THE CLOSE INTERPLAY OF TWO GENE EXPRESSION MACHINERIES
Authors
DEMO, Gabriel; Ahmed Adel I. H. HASSAN; Pradeep HIRIYUR NAGARAJ; Ludmila VESELÁ; Hassan ZAFAR; Lucie SLÁMOVÁ and Sylva BRABENCOVÁ
Edition
Czech Chemical Society Symposium Series - Annual meeting of the National Institute of Virology and Bacteriology (NIVB), 2022
Other information
Language
English
Type of outcome
Konferenční abstrakta
Country of publisher
Czech Republic
Confidentiality degree
is not subject to a state or trade secret
References:
Organization
Středoevropský technologický institut – Repository – Repository
ISSN
Keywords in English
mRNA; RNAP
Links
LX22NPO5103, research and development project.
Changed: 7/2/2023 04:36, RNDr. Daniel Jakubík
Abstract
V originále
In Bacteria, the transcribed messenger RNA (mRNA) can be directly attached to the first translating ribosome by creating a physical interaction between the ribosome and RNA polymerase (RNAP)1. The lead ribosome, in this transcription-translation complex, regulates the progression of transcription and protects the transcribed mRNA from premature transcription termination or mRNA degradation2. In the coupled system of transcription-translation the lead ribosome closely trails the RNAP, with rates of translation matching the transcription to support the efficient gene expression2.The direct interactions between RNAP and the translational machinery allow them to co-localize in bacterial cell and maintain the genome stability.
