D 2025

Scalable Counting of Minimal Trap Spaces and Fixed Points in Boolean Networks

KABIR, Mohimenul; Van-Giang TRINH; Samuel PASTVA a Kuldeep S. MEEL

Základní údaje

Originální název

Scalable Counting of Minimal Trap Spaces and Fixed Points in Boolean Networks

Autoři

KABIR, Mohimenul; Van-Giang TRINH; Samuel PASTVA a Kuldeep S. MEEL

Vydání

Dagstuhl, Germany, 31ST INTERNATIONAL CONFERENCE ON PRINCIPLES AND PRACTICE OF CONSTRAINT PROGRAMMING, CP 2025, od s. 1-26, 26 s. 2025

Nakladatel

SCHLOSS DAGSTUHL, LEIBNIZ CENTER INFORMATICS

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

elektronická verze "online"

Označené pro přenos do RIV

Ne

Organizace

Fakulta informatiky – Masarykova univerzita – Repozitář

ISSN

Klíčová slova anglicky

Computational systems biology; Boolean network; Fixed point; Trap space; Answer set counting; Projected counting; Abstract argumentation; Logic programming
Změněno: 7. 2. 2026 00:50, RNDr. Daniel Jakubík

Anotace

V originále

Boolean Networks (BNs) serve as a fundamental modeling framework for capturing complex dynamical systems across various domains, including systems biology, computational logic, and artificial intelligence. A crucial property of BNs is the presence of trap spaces - subspaces of the state space that, once entered, cannot be exited. Minimal trap spaces, in particular, play a significant role in analyzing the long-term behavior of BNs, making their efficient enumeration and counting essential. The fixed points in BNs are a special case of minimal trap spaces. In this work, we formulate several meaningful counting problems related to minimal trap spaces and fixed points in BNs. These problems provide valuable insights both within BN theory (e.g., in probabilistic reasoning and dynamical analysis) and in broader application areas, including systems biology, abstract argumentation, and logic programming. To address these computational challenges, we propose novel methods based on approximate answer set counting, leveraging techniques from answer set programming. Our approach efficiently approximates the number of minimal trap spaces and the number of fixed points without requiring exhaustive enumeration, making it particularly well-suited for large-scale BNs. Our experimental evaluation on an extensive and diverse set of benchmark instances shows that our methods significantly improve the feasibility of counting minimal trap spaces and fixed points, paving the way for new applications in BN analysis and beyond.

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