Some Levels of Plasma Free Fatty Acids and Amino Acids in the
Second Trimester Are Linked to Gestational Diabetes and Are
Predictive of Persisting Impaired Glucose Tolerance After
Delivery

CSLog in Log in (EduId)

Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to ...

Přehled o publikaci

J 2025

Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery

BARTÁKOVÁ, Vendula; Anna PLESKAČOVÁ; Lukáš PÁCAL; Monika SKRUTKOVÁ LANGMAJEROVÁ; Jindra SMUTNÁ et. al.

Basic information

Original name

Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery

Authors

Edition

JOURNAL OF CLINICAL MEDICINE, SWITZERLAND, MDPI, 2025, 2077-0383

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Switzerland

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.3390/jcm14134744

UT WoS

999

EID Scopus

999

Keywords in English

gestational diabetes mellitus; amino acids; free fatty acids

Links

LX22NPO5104, research and development project. NW24-01-00285, research and development project.

Changed: 18/7/2025 00:50, RNDr. Daniel Jakubík

Abstract

V originále

lt; 0.05, Spearman). Logistic regression model (using AAs, FFAs and BMI) identified higher citrulline and glutamate levels and lower tetradecenoic acid and choline as the best predictors for postpartum PGI. Some differences in AA levels were detected in women with macrosomic babies. Conclusions: Data support a possible link between GDM development and PGI after delivery and selected metabolite levels. The predictive potential of plasma FFAs and AAs levels on a diabetes risk in future life requires further validation.

Files attached

https://is.muni.cz/publication/2508837/Some_Levels_of_Plasma_Free_Fatty_Acids_and_Amino_Acids_in_the_Second_Trimester_Are_Linked_to_Gestational_Diabetes_and_Are_Predictive_of_Persisting_Impaired_Glucose_Tolerance_After_Delivery.pdf

Cite

BARTÁKOVÁ, Vendula; Anna PLESKAČOVÁ; Lukáš PÁCAL; Monika SKRUTKOVÁ LANGMAJEROVÁ; Jindra SMUTNÁ; Katarína CHALÁSOVÁ; Veronika ECLEROVÁ; Zdeněk GLATZ; Kateřina KAŇKOVÁ and Josef TOMANDL. Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery. JOURNAL OF CLINICAL MEDICINE. SWITZERLAND: MDPI, 2025, vol. 14, No 13, p. 1-15. ISSN 2077-0383. Available from: https://dx.doi.org/10.3390/jcm14134744.

@article{78448,
   author = {Bartáková, Vendula and Pleskačová, Anna and Pácal, Lukáš and Skrutková Langmajerová, Monika and Smutná, Jindra and Chalásová, Katarína and Eclerová, Veronika and Glatz, Zdeněk and Kaňková, Kateřina and TOMANDL, Josef},
   article_location = {SWITZERLAND},
   article_number = {13},
   doi = {http://dx.doi.org/10.3390/jcm14134744},
   keywords = {gestational diabetes mellitus; amino acids; free fatty acids},
   language = {eng},
   issn = {2077-0383},
   journal = {JOURNAL OF CLINICAL MEDICINE},
   title = {Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery},
   url = {https://www.mdpi.com/2077-0383/14/13/4744},
   volume = {14},
   year = {2025}
}

TY  - JOUR
ID  - 78448
AU  - Bartáková, Vendula - Pleskačová, Anna - Pácal, Lukáš - Skrutková Langmajerová, Monika - Smutná, Jindra - Chalásová, Katarína - Eclerová, Veronika - Glatz, Zdeněk - Kaňková, Kateřina - TOMANDL, Josef
PY  - 2025
TI  - Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery
JF  - JOURNAL OF CLINICAL MEDICINE
VL  - 14
IS  - 13
SP  - 1-15
EP  - 1-15
PB  - MDPI
SN  - 2077-0383
KW  - gestational diabetes mellitus
KW  - amino acids
KW  - free fatty acids
UR  - https://www.mdpi.com/2077-0383/14/13/4744
N2  - lt; 0.05, Spearman). Logistic regression model (using AAs, FFAs and BMI) identified higher citrulline and glutamate levels and lower tetradecenoic acid and choline as the best predictors for postpartum PGI. Some differences in AA levels were detected in women with macrosomic babies. Conclusions: Data support a possible link between GDM development and PGI after delivery and selected metabolite levels. The predictive potential of plasma FFAs and AAs levels on a diabetes risk in future life requires further validation.
ER  -

BARTÁKOVÁ, Vendula; Anna PLESKAČOVÁ; Lukáš PÁCAL; Monika SKRUTKOVÁ LANGMAJEROVÁ; Jindra SMUTNÁ; Katarína CHALÁSOVÁ; Veronika ECLEROVÁ; Zdeněk GLATZ; Kateřina KAŇKOVÁ and Josef TOMANDL. Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery. \textit{JOURNAL OF CLINICAL MEDICINE}. SWITZERLAND: MDPI, 2025, vol.~14, No~13, p.~1-15. ISSN~2077-0383. Available from: https://dx.doi.org/10.3390/jcm14134744.