Přehled o publikaci

Biomolecular condensates, which assemble in cells to regulate key biological processes, are challenging to study due to their inherently dynamic nature. In this talk, we will present our integrative multi-scale approach, which integrates light microscopy, electron cryomicroscopy, cryotomography, and coarse-grained simulations. Together, these methods reveal new insights into the molecular organization and biogenesis of a model RNA polymerase II condensate, shedding light on its structural complexity.