J 2024

Exploring BPA alternatives - Environmental levels and toxicity review

ADAMOVSKÝ, Ondřej, Ksenia J. GROH, Anna BIALK-BIELINSKA, Beate I. ESCHER, R. BEAUDOUIN et. al.

Basic information

Original name

Exploring BPA alternatives - Environmental levels and toxicity review

Authors

ADAMOVSKÝ, Ondřej (203 Czech Republic, guarantor, belonging to the institution), Ksenia J. GROH, Anna BIALK-BIELINSKA, Beate I. ESCHER, R. BEAUDOUIN, Liadys Mora LAGARES, Knut Erik TOLLEFSEN, Martina FENSKE, Ewa MULKIEWICZ, Nicolas CREUSOT, Anita SOSNOWSKA, Susana LOUREIRO, Jonny BEYER, Guillermo REPETTO, Alja STERN, Isabel LOPES, Marta MONTEIRO, Andrea ZIKOVA-KLOAS, Tina ELERSEK, Marjan VRACKO, Szymon ZDYBEL, Tomasz PUZYN, Weronika KOCZUR, Jane Ebsen MORTHORST, Henrik HOLBECH, Gunnar CARLSSON, Stefan ORN, Oscar HERRERO, Ayesha SIDDIQUE, Matthias LIESS, Georg BRAUN, Vanessa SREBNY, Bojana ZEGURA, Nathalie HINFRAY, Francois BRION, Dries KNAPEN, Ellen VANDEPUTTE, Evelyn STINCKENS, Lucia VERGAUWEN, Lars BEHRENDT, Maria Joa SILVA, Luděk BLÁHA (203 Czech Republic, belonging to the institution) and Katerina KYRIAKOPOULOU

Edition

Environment International, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2024, 0160-4120

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

is not subject to a state or trade secret

References:

RIV identification code

RIV/00216224:14310/24:00136670

Organization

Přírodovědecká fakulta – Repository – Repository

UT WoS

001252718400001

EID Scopus

2-s2.0-85195407523

Keywords in English

BPA alternatives; Biological activity; In silico; Invertebrates; Vertebrates

Links

GF23-13617L, research and development project. 101057014, interní kód Repo. 857560, interní kód Repo. RECETOX RI II, large research infrastructures.
Changed: 28/5/2025 00:50, RNDr. Daniel Jakubík

Abstract

V originále

Bisphenol A alternatives are manufactured as potentially less harmful substitutes of bisphenol A (BPA) that offer similar functionality. These alternatives are already in the market, entering the environment and thus raising ecological concerns. However, it can be expected that levels of BPA alternatives will dominate in the future, they are limited information on their environmental safety. The EU PARC project highlights BPA alternatives as priority chemicals and consolidates information on BPA alternatives, with a focus on environmental relevance and on the identification of the research gaps. The review highlighted aspects and future perspectives. In brief, an extension of environmental monitoring is crucial, extending it to cover BPA alternatives to track their levels and facilitate the timely implementation of mitigation measures. The biological activity has been studied for BPA alternatives, but in a non-systematic way and prioritized a limited number of chemicals. For several BPA alternatives, the data has already provided substantial evidence regarding their potential harm to the environment. We stress the importance of conducting more comprehensive assessments that go beyond the traditional reproductive studies and focus on overlooked relevant endpoints. Future research should also consider mixture effects, realistic environmental concentrations, and the long-term consequences on biota and ecosystems.

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