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@proceedings{60467,
author = {Černovská, Karolína and Porc, Jakub Paweł and Závacká, Kristýna and Stránská, Kamila and Adamová, Sabina and Ondroušková, Eva and Jarošová, Marie and Pospíšilová, Šárka and Plevová, Karla},
booktitle = {EMBL Conference Cancer Genomics 2023, Heidelberg, Německo},
keywords = {chromosomal rearrangements; chronic lymphocytic leukemia; topologically associated domains},
language = {eng},
title = {Resolving chromatin organization in chronic lymphocytic leukemia.},
url = {https://www.embl.org/about/info/course-and-conference-office/events/can23-01/},
year = {2023}
}
TY - CONF
ID - 60467
AU - Černovská, Karolína - Porc, Jakub Paweł - Závacká, Kristýna - Stránská, Kamila - Adamová, Sabina - Ondroušková, Eva - Jarošová, Marie - Pospíšilová, Šárka - Plevová, Karla
PY - 2023
TI - Resolving chromatin organization in chronic lymphocytic leukemia.
KW - chromosomal rearrangements
KW - chronic lymphocytic leukemia
KW - topologically associated domains
UR - https://www.embl.org/about/info/course-and-conference-office/events/can23-01/
N2 - The spatial chromatin organization has been recognized as essential for fundamental cell processes. Disruption of its hierarchical structure can be caused by chromosomal rearrangements, which, especially in cancer cells, lead to aberrant molecular signaling. We aim to study altered genome structure in chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults. We are particularly interested in the analysis of long-distance chromatin interactions and the formation of topologically associated domains (TADs), which might play a role in CLL pathogenesis.
ER -
ČERNOVSKÁ, Karolína, Jakub Paweł PORC, Kristýna ZÁVACKÁ, Kamila STRÁNSKÁ, Sabina ADAMOVÁ, Eva ONDROUŠKOVÁ, Marie JAROŠOVÁ, Šárka POSPÍŠILOVÁ a Karla PLEVOVÁ. Resolving chromatin organization in chronic lymphocytic leukemia. In \textit{EMBL Conference Cancer Genomics 2023, Heidelberg, Německo}. 2023.
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