Přehled o publikaci
2023
Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.
REIGL, Tomáš, Veronika NAVRKALOVÁ, Jakub Paweł PORC, Karol PÁL, Kamila STRÁNSKÁ et. al.Basic information
Original name
Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.
Authors
REIGL, Tomáš, Veronika NAVRKALOVÁ, Jakub Paweł PORC, Karol PÁL, Kamila STRÁNSKÁ, Šárka POSPÍŠILOVÁ and Karla PLEVOVÁ
Edition
CEITEC PhD Conference, 2023
Other information
Language
English
Type of outcome
Konferenční abstrakta
Country of publisher
Czech Republic
Confidentiality degree
is not subject to a state or trade secret
References:
Organization
Středoevropský technologický institut – Repository – Repository
Keywords in English
leukemia; LYmphoid NeXt-Generation Sequencing; LYNX;
Links
LM2018140, research and development project. LX22NPO5102, research and development project. NU21-08-00237, research and development project. NU22-08-00227, research and development project.
Changed: 25/3/2024 03:21, RNDr. Daniel Jakubík
Abstract
V originále
High throughput sequencing data analysis of IG/TR rearranged genes in leukemia clinical research', he has been involved in the development of several software projects, e.g.: LYNX (LYmphoid NeXt-Generation Sequencing) analytical software, CLLue, ARResT/Interrogate, ARResT/Subsets aka Encyclopedia of CLL Subsets. LYNX is a tailor-made bioinformatic tool for a new custom-designed capture-based NGS panel. With this tool, a user can analyze molecular markers, such as gene mutations, copy number variations, antigen receptor rearrangements, and translocations in the most common lymphoid malignancies. CLLue is an interactive web-based tool that allows users to perform a visual exploratory data analysis, identification of important and significant features in given groups based on statistical tests, and de novo clustering on their data.
