Přehled o publikaci
2023
Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.
REIGL, Tomáš; Veronika NAVRKALOVÁ; Jakub Paweł PORC; Karol PÁL; Kamila STRÁNSKÁ et. al.Basic information
Original name
Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.
Authors
REIGL, Tomáš; Veronika NAVRKALOVÁ; Jakub Paweł PORC; Karol PÁL; Kamila STRÁNSKÁ; Šárka POSPÍŠILOVÁ and Karla PLEVOVÁ
Edition
CEITEC PhD Conference, 2023
Other information
Language
English
Type of outcome
Konferenční abstrakta
Country of publisher
Czech Republic
Confidentiality degree
is not subject to a state or trade secret
References:
Organization
Středoevropský technologický institut – Repository – Repository
Keywords in English
leukemia; LYmphoid NeXt-Generation Sequencing; LYNX;
Links
LM2018140, research and development project. LX22NPO5102, research and development project. NU21-08-00237, research and development project. NU22-08-00227, research and development project.
Changed: 25/3/2024 03:21, RNDr. Daniel Jakubík
Abstract
V originále
High throughput sequencing data analysis of IG/TR rearranged genes in leukemia clinical research', he has been involved in the development of several software projects, e.g.: LYNX (LYmphoid NeXt-Generation Sequencing) analytical software, CLLue, ARResT/Interrogate, ARResT/Subsets aka Encyclopedia of CLL Subsets. LYNX is a tailor-made bioinformatic tool for a new custom-designed capture-based NGS panel. With this tool, a user can analyze molecular markers, such as gene mutations, copy number variations, antigen receptor rearrangements, and translocations in the most common lymphoid malignancies. CLLue is an interactive web-based tool that allows users to perform a visual exploratory data analysis, identification of important and significant features in given groups based on statistical tests, and de novo clustering on their data.
