Podrobný výpis o publikaci

@proceedings{60348,
   author = {Kurucová, Terézia and Réblová, Kamila and Vališová, Martina and Porc, Jakub Paweł and Navrkalová, Veronika and Pavlová, Šárka and Malčíková, Jitka and Plevová, Karla and Tichý, Boris and Doubek, Michael and Kotašková, Jana and Pospíšilová, Šárka},
   booktitle = {EHA 2023 in HemaSphere (2023)},
   keywords = {Chronic lymphocytic leukemia; single-cell RNA sequencing; relapse},
   language = {eng},
   title = {Single-cell RNA-sequencing enables tracking and characterization of rare CLL cells with the potential to cause refractoriness.},
   url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429134/},
   year = {2023}
}

TY  - CONF
ID  - 60348
AU  - Kurucová, Terézia - Réblová, Kamila - Vališová, Martina - Porc, Jakub Paweł - Navrkalová, Veronika - Pavlová, Šárka - Malčíková, Jitka - Plevová, Karla - Tichý, Boris - Doubek, Michael - Kotašková, Jana - Pospíšilová, Šárka
PY  - 2023
TI  - Single-cell RNA-sequencing enables tracking and characterization of rare CLL cells with the potential to cause refractoriness.
KW  - Chronic lymphocytic leukemia
KW  - single-cell RNA sequencing
KW  - relapse
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10429134/
N2  - Chronic lymphocytic leukemia (CLL) is considered an incurable disease due to the limited ability of current treatment options to completely eradicate leukemic cells. The therapy selection pressure favors the preferential proliferation of rare resistant cells, leading to recurrent relapses. Early detection of these rare cells holds the potential to assist in selecting appropriate therapy. To explore the possibility to identify and characterize rare populations of CLL cells resistant to treatment and causing relapses, and trace the presence of such cells during the disease course by single-cell RNA sequencing (scRNA-seq).
ER  - 

KURUCOVÁ, Terézia, Kamila RÉBLOVÁ, Martina VALIŠOVÁ, Jakub Paweł PORC, Veronika NAVRKALOVÁ, Šárka PAVLOVÁ, Jitka MALČÍKOVÁ, Karla PLEVOVÁ, Boris TICHÝ, Michael DOUBEK, Jana KOTAŠKOVÁ a Šárka POSPÍŠILOVÁ. Single-cell RNA-sequencing enables tracking and characterization of rare CLL cells with the potential to cause refractoriness. In \textit{EHA 2023 in HemaSphere (2023)}. 2023. ISSN~2572-9241.