MARQUEZ SANCHEZ - CARNERERO, Esther Maria, Marina RUSSO, Andreas Wolfgang JAKOB, Lucie MUCHOVA, Libor VÍTEK and Petr KLÁN. Effects of Substituents on Photophysical and CO-Photoreleasing Properties of 2,6-Substituted meso-Carboxy BODIPY Derivatives. CHEMISTRY-SWITZERLAND. BASEL: MDPI, 2021, vol. 3, No 1, p. 238-255. ISSN 2624-8549. Available from: https://dx.doi.org/10.3390/chemistry3010018. |
Other formats:
BibTeX
LaTeX
RIS
@article{48276, author = {Marquez Sanchez and Carnerero, Esther Maria and Russo, Marina and Jakob, Andreas Wolfgang and Muchova, Lucie and Vítek, Libor and Klán, Petr}, article_location = {BASEL}, article_number = {1}, doi = {http://dx.doi.org/10.3390/chemistry3010018}, keywords = {BODIPY; photochemistry; carbon monoxide; photorelease; carbon monoxide-releasing molecules}, language = {eng}, issn = {2624-8549}, journal = {CHEMISTRY-SWITZERLAND}, title = {Effects of Substituents on Photophysical and CO-Photoreleasing Properties of 2,6-Substituted meso-Carboxy BODIPY Derivatives}, url = {https://www.mdpi.com/2624-8549/3/1/18}, volume = {3}, year = {2021} }
TY - JOUR ID - 48276 AU - Marquez Sanchez - Carnerero, Esther Maria - Russo, Marina - Jakob, Andreas Wolfgang - Muchova, Lucie - Vítek, Libor - Klán, Petr PY - 2021 TI - Effects of Substituents on Photophysical and CO-Photoreleasing Properties of 2,6-Substituted meso-Carboxy BODIPY Derivatives JF - CHEMISTRY-SWITZERLAND VL - 3 IS - 1 SP - 238-255 EP - 238-255 PB - MDPI SN - 2624-8549 KW - BODIPY KW - photochemistry KW - carbon monoxide KW - photorelease KW - carbon monoxide-releasing molecules UR - https://www.mdpi.com/2624-8549/3/1/18 N2 - Carbon monoxide (CO) is an endogenously produced signaling molecule involved in the control of a vast array of physiological processes. One of the strategies to administer therapeutic amounts of CO is the precise spatial and temporal control over its release from photoactivatable CO-releasing molecules (photoCORMs). Here we present the synthesis and photophysical and photochemical properties of a small library of meso-carboxy BODIPY derivatives bearing different substituents at positions 2 and 6. We show that the nature of substituents has a major impact on both their photophysics and the efficiency of CO photorelease. CO was found to be efficiently released from pi -extended 2,6-arylethynyl BODIPY derivatives possessing absorption spectra shifted to a more biologically desirable wavelength range. Selected photoCORMs were subjected to in vitro experiments that did not reveal any serious toxic effects, suggesting their potential for further biological research. ER -
MARQUEZ SANCHEZ - CARNERERO, Esther Maria, Marina RUSSO, Andreas Wolfgang JAKOB, Lucie MUCHOVA, Libor VÍTEK and Petr KLÁN. Effects of Substituents on Photophysical and CO-Photoreleasing Properties of 2,6-Substituted meso-Carboxy BODIPY Derivatives. \textit{CHEMISTRY-SWITZERLAND}. BASEL: MDPI, 2021, vol.~3, No~1, p.~238-255. ISSN~2624-8549. Available from: https://dx.doi.org/10.3390/chemistry3010018.
|