ČTVERÁČKOVÁ, Lucie, Daniel JANČULA, Jan RAŠKA, Pavel BABICA a Iva SOVADINOVÁ. Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells. International Journal of Molecular Sciences. Basel: Multidisciplinary Digital Publishing Institute, 2020, roč. 21, č. 17, s. 1-21. ISSN 1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms21176069. |
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@article{45506, author = {Čtveráčková, Lucie and Jančula, Daniel and Raška, Jan and Babica, Pavel and Sovadinová, Iva}, article_location = {Basel}, article_number = {17}, doi = {http://dx.doi.org/10.3390/ijms21176069}, keywords = {gap junctional intercellular communication; gap junctions; hepatotoxicity; MAP-kinases Erk1; 2 activation; non-genomic mechanism; oval cells; phthalates; progenitor cells}, language = {eng}, issn = {1422-0067}, journal = {International Journal of Molecular Sciences}, title = {Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells}, url = {https://www.mdpi.com/1422-0067/21/17/6069}, volume = {21}, year = {2020} }
TY - JOUR ID - 45506 AU - Čtveráčková, Lucie - Jančula, Daniel - Raška, Jan - Babica, Pavel - Sovadinová, Iva PY - 2020 TI - Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells JF - International Journal of Molecular Sciences VL - 21 IS - 17 SP - 1-21 EP - 1-21 PB - Multidisciplinary Digital Publishing Institute SN - 1422-0067 KW - gap junctional intercellular communication KW - gap junctions KW - hepatotoxicity KW - MAP-kinases Erk1 KW - 2 activation KW - non-genomic mechanism KW - oval cells KW - phthalates KW - progenitor cells UR - https://www.mdpi.com/1422-0067/21/17/6069 N2 - gt;12 h), suggesting that GJIC dysregulation occurs via genomic mechanisms, or (bio)transformation. Overall, medium-chain phthalates rapidly affected the key tissue homeostatic mechanisms in the liver oval cell population via non-genomic pathways, which might contribute to the development of chronic liver toxicity and diseases. ER -
ČTVERÁČKOVÁ, Lucie, Daniel JANČULA, Jan RAŠKA, Pavel BABICA a Iva SOVADINOVÁ. Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells. \textit{International Journal of Molecular Sciences}. Basel: Multidisciplinary Digital Publishing Institute, 2020, roč.~21, č.~17, s.~1-21. ISSN~1422-0067. Dostupné z: https://dx.doi.org/10.3390/ijms21176069.
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