Twenty-five years of epilepsy surgery at a Central European
comprehensive epilepsy center-Trends in intervention delay and
outcomes

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Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in ...

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J 2023

Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in intervention delay and outcomes

VŠIANSKÝ, Vít, Milan BRÁZDIL, Ivan REKTOR, Irena DOLEŽALOVÁ, Jitka KOČVAROVÁ et. al.

Základní údaje

Originální název

Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in intervention delay and outcomes

Autoři

Vydání

Epilepsia Open, HOBOKEN, WILEY, 2023, 2470-9239

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Organizace

Lékařská fakulta – Masarykova univerzita – Repozitář

DOI

http://dx.doi.org/10.1002/epi4.12769

UT WoS

001004555400001

Klíčová slova anglicky

drug-resistant epilepsy; drug-resistant epilepsy epidemiology; drug-resistant epilepsy surgery

Návaznosti

LX22NPO5107, projekt VaV.

Změněno: 24. 1. 2024 03:13, RNDr. Daniel Jakubík

Anotace

V originále

lt; 0.001). For resections, better outcomes (ILAE scores 1a-2) have been achieved in extratemporal lesional (0%-21%-61%, P = 0.01, at least 2-year follow-up) patients. In temporal lesional patients, outcomes remained unchanged (at least 77% success rate). A longer duration of epilepsy predicted a less favorable outcome for resective procedures (P = 0.024) in patients with disease duration of less than 25 years. SignificanceThe spectrum of epilepsy surgery is shifting toward nonlesional and extratemporal cases. While success rates of extratemporal resections at our center are getting better, the average duration of epilepsy before surgical intervention is still very long and is not improving. This underscores the need for stronger collaboration between epileptologists and outpatient neurologists to ensure prompt and effective treatment for patients with drug-resistant epilepsy.

Přiložené soubory

https://is.muni.cz/publication/2291649/Twenty-five_years_of_epilepsy_surgery_at_a_Central_European_comprehensive_epilepsy_center-Trends_in_intervention_delay_and_outcomes.pdf

Citovat

VŠIANSKÝ, Vít, Milan BRÁZDIL, Ivan REKTOR, Irena DOLEŽALOVÁ, Jitka KOČVAROVÁ, Ondřej STRÝČEK, Jan HEMZA, Jan CHRASTINA, Eva BRICHTOVÁ, Ondřej HORÁK, Patrícia MUŽLAYOVÁ, Markéta HERMANOVÁ, Michal HENDRYCH a Martin PAIL. Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in intervention delay and outcomes. Epilepsia Open. HOBOKEN: WILEY, 2023, roč. 8, č. 3, s. 991-1001. ISSN 2470-9239. Dostupné z: https://dx.doi.org/10.1002/epi4.12769.

@article{56766,
   author = {Všianský, Vít and Brázdil, Milan and Rektor, Ivan and Doležalová, Irena and Kočvarová, Jitka and Strýček, Ondřej and Hemza, Jan and Chrastina, Jan and Brichtová, Eva and Horák, Ondřej and Mužlayová, Patrícia and Hermanová, Markéta and Hendrych, Michal and Pail, Martin},
   article_location = {HOBOKEN},
   article_number = {3},
   doi = {http://dx.doi.org/10.1002/epi4.12769},
   keywords = {drug-resistant epilepsy; drug-resistant epilepsy epidemiology; drug-resistant epilepsy surgery},
   language = {eng},
   issn = {2470-9239},
   journal = {Epilepsia Open},
   title = {Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in intervention delay and outcomes},
   url = {https://onlinelibrary.wiley.com/doi/full/10.1002/epi4.12769},
   volume = {8},
   year = {2023}
}

TY  - JOUR
ID  - 56766
AU  - Všianský, Vít - Brázdil, Milan - Rektor, Ivan - Doležalová, Irena - Kočvarová, Jitka - Strýček, Ondřej - Hemza, Jan - Chrastina, Jan - Brichtová, Eva - Horák, Ondřej - Mužlayová, Patrícia - Hermanová, Markéta - Hendrych, Michal - Pail, Martin
PY  - 2023
TI  - Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in intervention delay and outcomes
JF  - Epilepsia Open
VL  - 8
IS  - 3
SP  - 991-1001
EP  - 991-1001
PB  - WILEY
SN  - 2470-9239
KW  - drug-resistant epilepsy
KW  - drug-resistant epilepsy epidemiology
KW  - drug-resistant epilepsy surgery
UR  - https://onlinelibrary.wiley.com/doi/full/10.1002/epi4.12769
N2  - lt; 0.001). For resections, better outcomes (ILAE scores 1a-2) have been achieved in extratemporal lesional (0%-21%-61%, P = 0.01, at least 2-year follow-up) patients. In temporal lesional patients, outcomes remained unchanged (at least 77% success rate). A longer duration of epilepsy predicted a less favorable outcome for resective procedures (P = 0.024) in patients with disease duration of less than 25 years. SignificanceThe spectrum of epilepsy surgery is shifting toward nonlesional and extratemporal cases. While success rates of extratemporal resections at our center are getting better, the average duration of epilepsy before surgical intervention is still very long and is not improving. This underscores the need for stronger collaboration between epileptologists and outpatient neurologists to ensure prompt and effective treatment for patients with drug-resistant epilepsy.
ER  -

VŠIANSKÝ, Vít, Milan BRÁZDIL, Ivan REKTOR, Irena DOLEŽALOVÁ, Jitka KOČVAROVÁ, Ondřej STRÝČEK, Jan HEMZA, Jan CHRASTINA, Eva BRICHTOVÁ, Ondřej HORÁK, Patrícia MUŽLAYOVÁ, Markéta HERMANOVÁ, Michal HENDRYCH a Martin PAIL. Twenty-five years of epilepsy surgery at a Central European comprehensive epilepsy center-Trends in intervention delay and outcomes. \textit{Epilepsia Open}. HOBOKEN: WILEY, 2023, roč.~8, č.~3, s.~991-1001. ISSN~2470-9239. Dostupné z: https://dx.doi.org/10.1002/epi4.12769.