J 2025

Real-World Data From a Molecular Tumor Board-Assisted Cancer Care From a Single Center in The Czech Republic: Is Precision Oncology an Accessible Option, or a Privilege for a Minority of Patients?

EID, Michal; Markéta BEDNAŘÍKOVÁ; Jakub VLAŽNÝ; Jitka HAUSNEROVÁ; Renata TASLEROVÁ et. al.

Basic information

Original name

Real-World Data From a Molecular Tumor Board-Assisted Cancer Care From a Single Center in The Czech Republic: Is Precision Oncology an Accessible Option, or a Privilege for a Minority of Patients?

Authors

EID, Michal; Markéta BEDNAŘÍKOVÁ; Jakub VLAŽNÝ; Jitka HAUSNEROVÁ; Renata TASLEROVÁ; Sára VILMANOVÁ; Martina JELÍNKOVÁ; Alena HOMOLOVÁ; Martin GRYC; Jakub TRIZULJAK; Zdeněk PAVLOVSKÝ; Štěpán TUČEK; Dagmar BRANČÍKOVÁ; Monika BRATOVÁ; Tomáš ROHAN; Zdeněk KALA; Zdeněk KRÁL; Jiří MAYER; Adam SVOBODNÍK and Ondřej SLABÝ

Edition

Cancer Medicine, Hoboken, Sons Ltd. 2025, 2045-7634

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

United States of America

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

https://doi.org/10.1002/cam4.71119

UT WoS

001543062700001

EID Scopus

2-s2.0-105012466693

Keywords in English

biomarkers; cancer genetics; next-generation sequencing; target therapy

Links

LM2018132, research and development project. LX22NPO5102, research and development project. MUNI/A/1685/2024, interní kód Repo. CZECRIN IV, large research infrastructures.
Changed: 15/10/2025 00:51, RNDr. Daniel Jakubík

Abstract

In the original language

gt;= 1.3 was observed in 29 (41.4%) of the 70 evaluable pretreated patients.ConclusionThis is the first study to report on a real-world MTB cohort from the Czech Republic, demonstrating a diagnostic yield comparable to previously published studies, good availability of recommended drugs, and clinical benefit in evaluable patients.
Displayed: 18/12/2025 09:26