The impact of cardiogenic shock and out-of-hospital cardiac
arrest on the outcome of acute myocardial infarction: a
national-level analysis

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The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute ...

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J 2025

The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute myocardial infarction: a national-level analysis

TOMASOV, Pavol; Zuzana MOTOVSKA; Ota HLINOMAZ; Petr KALA; Marek SRAMKO et. al.

Basic information

Original name

The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute myocardial infarction: a national-level analysis

Authors

Edition

Internal and emergency medicine, Milan, Springer-Verlag Italia, 2025, 1828-0447

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Italy

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.1007/s11739-025-03984-6

UT WoS

001507761100001

EID Scopus

2-s2.0-105008227721

Keywords in English

Acute myocardial infarction; Out-of-hospital cardiac arrest; Cardiogenic shock; Outcome; Predictors

Links

LX22NPO5104, research and development project. NV19-02-00086, research and development project.

Changed: 8/7/2025 00:50, RNDr. Daniel Jakubík

Abstract

V originále

Cardiogenic shock (CS) and out-of-hospital cardiac arrest (OHCA) are events with profound implications for patient outcomes. We aim to analyze the predictors of CS and OHCA in patients with acute myocardial infarction and their effects on mortality. The analysis is based on data from a national registry between 2016 and 2020. A total of 23,703 patients with ST-elevation myocardial infarction (STEMI) were analyzed: (A) patients without CS and OHCA (19,590), (B) after OHCA (2,262), (C) with CS (713), and (D) after OHCA with CS (1,138). Patients after OHCA without CS had the lowest mean age [62.0 (+/- 12.6) years], while patients with CS without OHCA were the oldest [68.8 (+/- 11.8) years] and had the highest proportions of comorbidities. CS was a predictor of 30-day and 1-year mortality, with odds ratios [OR; 95% confidence intervals (CI)] of 5.52 (4.51; 6.75) and 4.66 (3.87; 5.61) for patients after OHCA, and OR (95% CI) 9.28 (7.56; 11.38) and 7.33 (6.04; 8.89) for those without OHCA. For overall survival up to 30 days and in comparison to patients without CS and OHCA, the hazard ratios (95% CI) was 2.77 (2.40; 3.20) for patients with OHCA only, 14.36 (12.57; 16.40) for patients with CS only, and 16.96 (15.19; 18.92) for patients with both CS and OHCA. OHCA altered the 30-day mortality risk after STEMI for both patients with and without CS. CS is a predictor of both 30-day and 1-year mortality in patients with STEMI, irrespective of OHCA status.

Files attached

https://is.muni.cz/publication/2507546/The_impact_of_cardiogenic_shock_and_out-of-hospital_cardiac_arrest_on_the_outcome_of_acute_myocardial_infarction_a_national-level_analysis.pdf

Cite

TOMASOV, Pavol; Zuzana MOTOVSKA; Ota HLINOMAZ; Petr KALA; Marek SRAMKO; Jan MROZEK; Milan HROMADKA; Jan PRECEK; Josef BIS; Jan MATEJKA; Tamilla MUZAFAROVA; Pavel CERVINKA; Ales KOVARIK; Libor SKNOURIL; Zdenek COUFAL and Jiří JARKOVSKÝ. The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute myocardial infarction: a national-level analysis. Internal and emergency medicine. Milan: Springer-Verlag Italia, 2025, 11 pp. ISSN 1828-0447. Available from: https://dx.doi.org/10.1007/s11739-025-03984-6.

@article{77534,
   author = {Tomasov, Pavol and Motovska, Zuzana and Hlinomaz, Ota and Kala, Petr and Sramko, Marek and Mrozek, Jan and Hromadka, Milan and Precek, Jan and Bis, Josef and Matejka, Jan and Muzafarova, Tamilla and Cervinka, Pavel and Kovarik, Ales and Sknouril, Libor and Coufal, Zdenek and Jarkovský, Jiří},
   article_location = {Milan},
   doi = {http://dx.doi.org/10.1007/s11739-025-03984-6},
   keywords = {Acute myocardial infarction; Out-of-hospital cardiac arrest; Cardiogenic shock; Outcome; Predictors},
   language = {eng},
   issn = {1828-0447},
   journal = {Internal and emergency medicine},
   title = {The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute myocardial infarction: a national-level analysis},
   url = {https://link.springer.com/article/10.1007/s11739-025-03984-6},
   year = {2025}
}

TY  - JOUR
ID  - 77534
AU  - Tomasov, Pavol - Motovska, Zuzana - Hlinomaz, Ota - Kala, Petr - Sramko, Marek - Mrozek, Jan - Hromadka, Milan - Precek, Jan - Bis, Josef - Matejka, Jan - Muzafarova, Tamilla - Cervinka, Pavel - Kovarik, Ales - Sknouril, Libor - Coufal, Zdenek - Jarkovský, Jiří
PY  - 2025
TI  - The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute myocardial infarction: a national-level analysis
JF  - Internal and emergency medicine
PB  - Springer-Verlag Italia
SN  - 1828-0447
KW  - Acute myocardial infarction
KW  - Out-of-hospital cardiac arrest
KW  - Cardiogenic shock
KW  - Outcome
KW  - Predictors
UR  - https://link.springer.com/article/10.1007/s11739-025-03984-6
N2  - Cardiogenic shock (CS) and out-of-hospital cardiac arrest (OHCA) are events with profound implications for patient outcomes. We aim to analyze the predictors of CS and OHCA in patients with acute myocardial infarction and their effects on mortality. The analysis is based on data from a national registry between 2016 and 2020. A total of 23,703 patients with ST-elevation myocardial infarction (STEMI) were analyzed: (A) patients without CS and OHCA (19,590), (B) after OHCA (2,262), (C) with CS (713), and (D) after OHCA with CS (1,138). Patients after OHCA without CS had the lowest mean age [62.0 (+/- 12.6) years], while patients with CS without OHCA were the oldest [68.8 (+/- 11.8) years] and had the highest proportions of comorbidities. CS was a predictor of 30-day and 1-year mortality, with odds ratios [OR; 95% confidence intervals (CI)] of 5.52 (4.51; 6.75) and 4.66 (3.87; 5.61) for patients after OHCA, and OR (95% CI) 9.28 (7.56; 11.38) and 7.33 (6.04; 8.89) for those without OHCA. For overall survival up to 30 days and in comparison to patients without CS and OHCA, the hazard ratios (95% CI) was 2.77 (2.40; 3.20) for patients with OHCA only, 14.36 (12.57; 16.40) for patients with CS only, and 16.96 (15.19; 18.92) for patients with both CS and OHCA. OHCA altered the 30-day mortality risk after STEMI for both patients with and without CS. CS is a predictor of both 30-day and 1-year mortality in patients with STEMI, irrespective of OHCA status.
ER  -

TOMASOV, Pavol; Zuzana MOTOVSKA; Ota HLINOMAZ; Petr KALA; Marek SRAMKO; Jan MROZEK; Milan HROMADKA; Jan PRECEK; Josef BIS; Jan MATEJKA; Tamilla MUZAFAROVA; Pavel CERVINKA; Ales KOVARIK; Libor SKNOURIL; Zdenek COUFAL and Jiří JARKOVSKÝ. The impact of cardiogenic shock and out-of-hospital cardiac arrest on the outcome of acute myocardial infarction: a national-level analysis. \textit{Internal and emergency medicine}. Milan: Springer-Verlag Italia, 2025, 11 pp. ISSN~1828-0447. Available from: https://dx.doi.org/10.1007/s11739-025-03984-6.