Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry
Authors
ELSHORBAGY, Amany, Antonio J VALLEJO-VAZ, Fotios BARKAS, Alexander R M LYONS, Christophe A T STEVENS, Kanika I DHARMAYAT, Alberico L CATAPANO, Tomáš FREIBERGER, G Kees HOVINGH, Pedro MATA, Frederick J RAAL, Raul D SANTOS, Handrean SORAN, Gerald F WATTS, Marianne ABIFADEL, Carlos A AGUILAR-SALINAS, Khalid F ALHABIB, Mutaz ALKHNIFSAWI, Wael ALMAHMEED, Fahad ALNOURI, Rodrigo ALONSO, Khalid AL-RASADI, Ahmad AL-SARRAF, Marcello ARCA, Tester F ASHAVAID, Maurizio AVERNA, Maciej BANACH, Marianne BECKER, Christoph J BINDER, Mafalda BOURBON, Liam R BRUNHAM, Krzysztof CHLEBUS, Pablo CORRAL, Diogo CRUZ, Kairat DAVLETOV, Olivier S DESCAMPS, Bambang DWIPUTRA, Marat EZHOV, Urh GROSELJ, Mariko HARADA-SHIBA, Kirsten B HOLVEN, Steve E HUMPHRIES, Meral KAYIKCIOGLU, Weerapan KHOVIDHUNKIT, Katarina LALIC, Gustavs LATKOVSKIS, Ulrich LAUFS, Evangelos LIBEROPOULOS, Marcos M LIMA-MARTINEZ, Vincent MAHER, A David MARAIS, Winfried MAERZ, Erkin MIRRAKHIMOV, Andre R MISEREZ, Olena MITCHENKO, Hapizah NAWAWI, Borge G NORDESTGAARD, Andrie G PANAYIOTOU, Gyoergy PARAGH, Zaneta PETRULIONIENE, Belma POJSKIC, Arman POSTADZHIYAN, Ashraf REDA, Zeljko REINER, Ximena REYES, Fouzia SADIQ, Wilson Ehidiamen SADOH, Heribert SCHUNKERT, Aleksandr B SHEK, Erik STROES, Ta-Chen SU, Tavintharan SUBRAMANIAM, Andrey V SUSEKOV, Myra TILNEY, Brian TOMLINSON, Thanh Huong TRUONG, Alexandros D TSELEPIS, Anne TYBJAERG-HANSEN, Alejandra VAZQUEZ-CARDENAS, Margus VIIGIMAA, Branislav VOHNOUT, Shizuya YAMASHITA and Kausik K RAY
Edition
European heart journal, Oxford, Oxford University Press, 2025, 0195-668X
Other information
Language
English
Type of outcome
Article in a journal
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Background and Aims Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.
ELSHORBAGY, Amany, Antonio J VALLEJO-VAZ, Fotios BARKAS, Alexander R M LYONS, Christophe A T STEVENS, Kanika I DHARMAYAT, Alberico L CATAPANO, Tomáš FREIBERGER, G Kees HOVINGH, Pedro MATA, Frederick J RAAL, Raul D SANTOS, Handrean SORAN, Gerald F WATTS, Marianne ABIFADEL, Carlos A AGUILAR-SALINAS, Khalid F ALHABIB, Mutaz ALKHNIFSAWI, Wael ALMAHMEED, Fahad ALNOURI, Rodrigo ALONSO, Khalid AL-RASADI, Ahmad AL-SARRAF, Marcello ARCA, Tester F ASHAVAID, Maurizio AVERNA, Maciej BANACH, Marianne BECKER, Christoph J BINDER, Mafalda BOURBON, Liam R BRUNHAM, Krzysztof CHLEBUS, Pablo CORRAL, Diogo CRUZ, Kairat DAVLETOV, Olivier S DESCAMPS, Bambang DWIPUTRA, Marat EZHOV, Urh GROSELJ, Mariko HARADA-SHIBA, Kirsten B HOLVEN, Steve E HUMPHRIES, Meral KAYIKCIOGLU, Weerapan KHOVIDHUNKIT, Katarina LALIC, Gustavs LATKOVSKIS, Ulrich LAUFS, Evangelos LIBEROPOULOS, Marcos M LIMA-MARTINEZ, Vincent MAHER, A David MARAIS, Winfried MAERZ, Erkin MIRRAKHIMOV, Andre R MISEREZ, Olena MITCHENKO, Hapizah NAWAWI, Borge G NORDESTGAARD, Andrie G PANAYIOTOU, Gyoergy PARAGH, Zaneta PETRULIONIENE, Belma POJSKIC, Arman POSTADZHIYAN, Ashraf REDA, Zeljko REINER, Ximena REYES, Fouzia SADIQ, Wilson Ehidiamen SADOH, Heribert SCHUNKERT, Aleksandr B SHEK, Erik STROES, Ta-Chen SU, Tavintharan SUBRAMANIAM, Andrey V SUSEKOV, Myra TILNEY, Brian TOMLINSON, Thanh Huong TRUONG, Alexandros D TSELEPIS, Anne TYBJAERG-HANSEN, Alejandra VAZQUEZ-CARDENAS, Margus VIIGIMAA, Branislav VOHNOUT, Shizuya YAMASHITA and Kausik K RAY. Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry. European heart journal. Oxford: Oxford University Press, 2025, 14 pp. ISSN 0195-668X. Available from: https://dx.doi.org/10.1093/eurheartj/ehae791.
@article{70806, author = {Elshorbagy, Amany and VallejoandVaz, Antonio J and Barkas, Fotios and Lyons, Alexander R M and Stevens, Christophe A T and Dharmayat, Kanika I and Catapano, Alberico L and Freiberger, Tomáš and Hovingh, G Kees and Mata, Pedro and Raal, Frederick J and Santos, Raul D and Soran, Handrean and Watts, Gerald F and Abifadel, Marianne and AguilarandSalinas, Carlos A and Alhabib, Khalid F and Alkhnifsawi, Mutaz and Almahmeed, Wael and Alnouri, Fahad and Alonso, Rodrigo and AlandRasadi, Khalid and AlandSarraf, Ahmad and Arca, Marcello and Ashavaid, Tester F and Averna, Maurizio and Banach, Maciej and Becker, Marianne and Binder, Christoph J and Bourbon, Mafalda and Brunham, Liam R and Chlebus, Krzysztof and Corral, Pablo and Cruz, Diogo and Davletov, Kairat and Descamps, Olivier S and Dwiputra, Bambang and Ezhov, Marat and Groselj, Urh and HaradaandShiba, Mariko and Holven, Kirsten B and Humphries, Steve E and Kayikcioglu, Meral and Khovidhunkit, Weerapan and Lalic, Katarina and Latkovskis, Gustavs and Laufs, Ulrich and Liberopoulos, Evangelos and LimaandMartinez, Marcos M and Maher, Vincent and Marais, A David and Maerz, Winfried and Mirrakhimov, Erkin and Miserez, Andre R and Mitchenko, Olena and Nawawi, Hapizah and Nordestgaard, Borge G and Panayiotou, Andrie G and Paragh, Gyoergy and Petrulioniene, Zaneta and Pojskic, Belma and Postadzhiyan, Arman and Reda, Ashraf and Reiner, Zeljko and Reyes, Ximena and Sadiq, Fouzia and Sadoh, Wilson Ehidiamen and Schunkert, Heribert and Shek, Aleksandr B and Stroes, Erik and Su, TaandChen and Subramaniam, Tavintharan and Susekov, Andrey V and Tilney, Myra and Tomlinson, Brian and Truong, Thanh Huong and Tselepis, Alexandros D and TybjaergandHansen, Anne and VazquezandCardenas, Alejandra and Viigimaa, Margus and Vohnout, Branislav and Yamashita, Shizuya and Ray, Kausik K}, article_location = {Oxford}, doi = {http://dx.doi.org/10.1093/eurheartj/ehae791}, keywords = {Dyslipidaemia; Adiposity; Insulin resistance; Atherosclerosis}, language = {eng}, issn = {0195-668X}, journal = {European heart journal}, title = {Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry}, url = {https://academic.oup.com/eurheartj/article/46/12/1127/7933169?login=true}, year = {2025} }
TY - JOUR ID - 70806 AU - Elshorbagy, Amany - Vallejo-Vaz, Antonio J - Barkas, Fotios - Lyons, Alexander R M - Stevens, Christophe A T - Dharmayat, Kanika I - Catapano, Alberico L - Freiberger, Tomáš - Hovingh, G Kees - Mata, Pedro - Raal, Frederick J - Santos, Raul D - Soran, Handrean - Watts, Gerald F - Abifadel, Marianne - Aguilar-Salinas, Carlos A - Alhabib, Khalid F - Alkhnifsawi, Mutaz - Almahmeed, Wael - Alnouri, Fahad - Alonso, Rodrigo - Al-Rasadi, Khalid - Al-Sarraf, Ahmad - Arca, Marcello - Ashavaid, Tester F - Averna, Maurizio - Banach, Maciej - Becker, Marianne - Binder, Christoph J - Bourbon, Mafalda - Brunham, Liam R - Chlebus, Krzysztof - Corral, Pablo - Cruz, Diogo - Davletov, Kairat - Descamps, Olivier S - Dwiputra, Bambang - Ezhov, Marat - Groselj, Urh - Harada-Shiba, Mariko - Holven, Kirsten B - Humphries, Steve E - Kayikcioglu, Meral - Khovidhunkit, Weerapan - Lalic, Katarina - Latkovskis, Gustavs - Laufs, Ulrich - Liberopoulos, Evangelos - Lima-Martinez, Marcos M - Maher, Vincent - Marais, A David - Maerz, Winfried - Mirrakhimov, Erkin - Miserez, Andre R - Mitchenko, Olena - Nawawi, Hapizah - Nordestgaard, Borge G - Panayiotou, Andrie G - Paragh, Gyoergy - Petrulioniene, Zaneta - Pojskic, Belma - Postadzhiyan, Arman - Reda, Ashraf - Reiner, Zeljko - Reyes, Ximena - Sadiq, Fouzia - Sadoh, Wilson Ehidiamen - Schunkert, Heribert - Shek, Aleksandr B - Stroes, Erik - Su, Ta-Chen - Subramaniam, Tavintharan - Susekov, Andrey V - Tilney, Myra - Tomlinson, Brian - Truong, Thanh Huong - Tselepis, Alexandros D - Tybjaerg-Hansen, Anne - Vazquez-Cardenas, Alejandra - Viigimaa, Margus - Vohnout, Branislav - Yamashita, Shizuya - Ray, Kausik K PY - 2025 TI - Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry JF - European heart journal PB - Oxford University Press SN - 0195-668X KW - Dyslipidaemia KW - Adiposity KW - Insulin resistance KW - Atherosclerosis UR - https://academic.oup.com/eurheartj/article/46/12/1127/7933169?login=true N2 - Background and Aims Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear. ER -
ELSHORBAGY, Amany, Antonio J VALLEJO-VAZ, Fotios BARKAS, Alexander R M LYONS, Christophe A T STEVENS, Kanika I DHARMAYAT, Alberico L CATAPANO, Tomáš FREIBERGER, G Kees HOVINGH, Pedro MATA, Frederick J RAAL, Raul D SANTOS, Handrean SORAN, Gerald F WATTS, Marianne ABIFADEL, Carlos A AGUILAR-SALINAS, Khalid F ALHABIB, Mutaz ALKHNIFSAWI, Wael ALMAHMEED, Fahad ALNOURI, Rodrigo ALONSO, Khalid AL-RASADI, Ahmad AL-SARRAF, Marcello ARCA, Tester F ASHAVAID, Maurizio AVERNA, Maciej BANACH, Marianne BECKER, Christoph J BINDER, Mafalda BOURBON, Liam R BRUNHAM, Krzysztof CHLEBUS, Pablo CORRAL, Diogo CRUZ, Kairat DAVLETOV, Olivier S DESCAMPS, Bambang DWIPUTRA, Marat EZHOV, Urh GROSELJ, Mariko HARADA-SHIBA, Kirsten B HOLVEN, Steve E HUMPHRIES, Meral KAYIKCIOGLU, Weerapan KHOVIDHUNKIT, Katarina LALIC, Gustavs LATKOVSKIS, Ulrich LAUFS, Evangelos LIBEROPOULOS, Marcos M LIMA-MARTINEZ, Vincent MAHER, A David MARAIS, Winfried MAERZ, Erkin MIRRAKHIMOV, Andre R MISEREZ, Olena MITCHENKO, Hapizah NAWAWI, Borge G NORDESTGAARD, Andrie G PANAYIOTOU, Gyoergy PARAGH, Zaneta PETRULIONIENE, Belma POJSKIC, Arman POSTADZHIYAN, Ashraf REDA, Zeljko REINER, Ximena REYES, Fouzia SADIQ, Wilson Ehidiamen SADOH, Heribert SCHUNKERT, Aleksandr B SHEK, Erik STROES, Ta-Chen SU, Tavintharan SUBRAMANIAM, Andrey V SUSEKOV, Myra TILNEY, Brian TOMLINSON, Thanh Huong TRUONG, Alexandros D TSELEPIS, Anne TYBJAERG-HANSEN, Alejandra VAZQUEZ-CARDENAS, Margus VIIGIMAA, Branislav VOHNOUT, Shizuya YAMASHITA and Kausik K RAY. Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry. \textit{European heart journal}. Oxford: Oxford University Press, 2025, 14 pp. ISSN~0195-668X. Available from: https://dx.doi.org/10.1093/eurheartj/ehae791.
