Přehled o publikaci
2024
Evolutionary Divergence in Hymenoptera and Lepidoptera Telomerase RNAs: A Shift from the Norm in Animal TR Biogenesis
FAJKUS, Petr; Andrew NELSON; Agata Magdalena KILAR; Michal FRANEK; Eva SYKOROVA et al.Basic information
Original name
Evolutionary Divergence in Hymenoptera and Lepidoptera Telomerase RNAs: A Shift from the Norm in Animal TR Biogenesis
Authors
FAJKUS, Petr; Andrew NELSON; Agata Magdalena KILAR; Michal FRANEK; Eva SYKOROVA; Vratislav PESKA and Jiří FAJKUS
Edition
EMBO Workshop: Telomere function and evolution in health and disease, Rome, Italy, 2024, 2024
Other information
Language
English
Type of outcome
Konferenční abstrakta
Country of publisher
Italy
Confidentiality degree
is not subject to a state or trade secret
References:
Marked to be transferred to RIV
No
Organization
Středoevropský technologický institut – Repository – Repository
Keywords in English
telomerase RNAs; polymerase III; insect; Lepidoptera; evolution; biogenesis
Links
EH22_008/0004581, research and development project. GX20-01331X, research and development project.
Changed: 20/3/2025 00:51, RNDr. Daniel Jakubík
Abstract
In the original language
Unlike typical animal TRs, which are transcribed by RNA Polymerase II, the TRs in Hymenoptera and Lepidoptera insects display characteristics similar to TRs in plants and ciliates, transcribed by RNA Polymerase III under the control of type 3 promoters. This significant deviation in TR biogenesis challenges the previously assumed monophyletic origin of TRs in animals and suggests an evolutionary shift in TR type and biogenesis within Arthropods. This discovery not only questions the uniformity of TR evolution across animals but also highlights the evolutionary flexibility in telomere biology, particularly in the context of insect genomic stability and telomere maintenance mechanisms.
