Přehled o publikaci
2024
High-Resolution Imaging of Transient RNA Polymerase II Biomolecular Condensates
ŠTEFL, RichardBasic information
Original name
High-Resolution Imaging of Transient RNA Polymerase II Biomolecular Condensates
Authors
ŠTEFL, Richard
Edition
Correlative Materials Characterization Workshop 2024, Dresden, 2024
Other information
Language
English
Type of outcome
Presentations at conferences
Country of publisher
Germany
Confidentiality degree
is not subject to a state or trade secret
References:
Organization
Středoevropský technologický institut – Repository – Repository
Keywords in English
RNA polymerase II; biomolecular condensates; light microscopy; Cryo-EM; cryotomography; coarse-grained simulations
Links
EH22_008/0004575, research and development project.
Changed: 11/2/2025 00:50, RNDr. Daniel Jakubík
Abstract
V originále
Biomolecular condensates, which assemble in cells to regulate key biological processes, are challenging to study due to their inherently dynamic nature. In this talk, we will present our integrative multi-scale approach, which integrates light microscopy, electron cryomicroscopy, cryotomography, and coarse-grained simulations. Together, these methods reveal new insights into the molecular organization and biogenesis of a model RNA polymerase II condensate, shedding light on its structural complexity.