J
2025
Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial
BURKOŇ, Petr; Iveta SELINGEROVÁ; Miroslav VRZAL; Miloš HOLÁNEK; Oldřich COUFAL et. al.
Basic information
Original name
Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial
Authors
BURKOŇ, Petr; Iveta SELINGEROVÁ; Miroslav VRZAL; Miloš HOLÁNEK; Oldřich COUFAL; Kateřina POLÁCHOVÁ; Vera ANDRASKOVA; Sachin R JHAWAR; Pavel ŠLAMPA; Tomáš KAZDA and Marek SLÁVIK
Edition
SCIENTIFIC REPORTS, England, NATURE PORTFOLIO, 2025, 2045-2322
Other information
Type of outcome
Article in a journal
Country of publisher
Germany
Confidentiality degree
is not subject to a state or trade secret
Organization
Lékařská fakulta – Repository – Repository
EID Scopus
2-s2.0-85215102805
Keywords in English
Early breast Cancer; Adjuvant radiotherapy; Accelerated partial breast irradiation; Whole breast irradiation; Health-related quality of life; QoL questionnaires; Clinical trial questionnaires
Links
LM2023033, research and development project. LM2023049, research and development project. LX22NPO5102, research and development project. CZECRIN IV, large research infrastructures.
V originále
lt; 0.001) scales at M0, with higher scores in the WBI arm. During follow-up, scores on symptoms scales returned to at least the baseline values. Early BC patients treated with APBI showed non-inferior short-term and late HRQoL outcomes compared to hypo-WBI. In addition to previous findings regarding toxicity, promising pain and breast symptoms results, suggest that APBI should be strongly considered as a treatment option for selected low-risk patients. Trial registration NCT06007118, August 23, 2023 (retrospectively registered).
Displayed: 4/8/2025 08:56