Quality of life in early breast cancer patients after adjuvant
accelerated partial-breast irradiation (APBI) in randomized
trial

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Quality of life in early breast cancer patients after adjuvant accelerated partial-breast ...

Přehled o publikaci

J 2025

Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial

BURKOŇ, Petr, Iveta SELINGEROVÁ, Miroslav VRZAL, Miloš HOLÁNEK, Oldřich COUFAL et. al.

Basic information

Original name

Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial

Authors

BURKOŇ, Petr, Iveta SELINGEROVÁ, Miroslav VRZAL, Miloš HOLÁNEK, Oldřich COUFAL, Kateřina POLÁCHOVÁ, Vera ANDRASKOVA, Sachin R JHAWAR, Pavel ŠLAMPA, Tomáš KAZDA and Marek SLÁVIK

Edition

SCIENTIFIC REPORTS, England, NATURE PORTFOLIO, 2025, 2045-2322

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Germany

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.1038/s41598-025-85342-2

UT WoS

001394278800005

EID Scopus

2-s2.0-85215102805

Keywords in English

Early breast Cancer; Adjuvant radiotherapy; Accelerated partial breast irradiation; Whole breast irradiation; Health-related quality of life; QoL questionnaires; Clinical trial questionnaires

Links

LM2023033, research and development project. LM2023049, research and development project. LX22NPO5102, research and development project. CZECRIN IV, large research infrastructures.

Changed: 26/3/2025 00:50, RNDr. Daniel Jakubík

Abstract

V originále

lt; 0.001) scales at M0, with higher scores in the WBI arm. During follow-up, scores on symptoms scales returned to at least the baseline values. Early BC patients treated with APBI showed non-inferior short-term and late HRQoL outcomes compared to hypo-WBI. In addition to previous findings regarding toxicity, promising pain and breast symptoms results, suggest that APBI should be strongly considered as a treatment option for selected low-risk patients. Trial registration NCT06007118, August 23, 2023 (retrospectively registered).

Files attached

https://is.muni.cz/publication/2474639/Quality_of_life_in_early_breast_cancer_patients_after_adjuvant_accelerated_partial-breast_irradiation__APBI__in_randomized_trial.pdf

Cite

BURKOŇ, Petr, Iveta SELINGEROVÁ, Miroslav VRZAL, Miloš HOLÁNEK, Oldřich COUFAL, Kateřina POLÁCHOVÁ, Vera ANDRASKOVA, Sachin R JHAWAR, Pavel ŠLAMPA, Tomáš KAZDA and Marek SLÁVIK. Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial. SCIENTIFIC REPORTS. England: NATURE PORTFOLIO, 2025, vol. 15, No 1, p. 1-12. ISSN 2045-2322. Available from: https://dx.doi.org/10.1038/s41598-025-85342-2.

@article{67730,
   author = {Burkoň, Petr and Selingerová, Iveta and Vrzal, Miroslav and Holánek, Miloš and Coufal, Oldřich and Poláchová, Kateřina and Andraskova, Vera and Jhawar, Sachin R and Šlampa, Pavel and Kazda, Tomáš and Slávik, Marek},
   article_location = {England},
   article_number = {1},
   doi = {http://dx.doi.org/10.1038/s41598-025-85342-2},
   keywords = {Early breast Cancer; Adjuvant radiotherapy; Accelerated partial breast irradiation; Whole breast irradiation; Health-related quality of life; QoL questionnaires; Clinical trial questionnaires},
   language = {eng},
   issn = {2045-2322},
   journal = {SCIENTIFIC REPORTS},
   title = {Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial},
   url = {https://www.nature.com/articles/s41598-025-85342-2},
   volume = {15},
   year = {2025}
}

TY  - JOUR
ID  - 67730
AU  - Burkoň, Petr - Selingerová, Iveta - Vrzal, Miroslav - Holánek, Miloš - Coufal, Oldřich - Poláchová, Kateřina - Andraskova, Vera - Jhawar, Sachin R - Šlampa, Pavel - Kazda, Tomáš - Slávik, Marek
PY  - 2025
TI  - Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial
JF  - SCIENTIFIC REPORTS
VL  - 15
IS  - 1
SP  - 1-12
EP  - 1-12
PB  - NATURE PORTFOLIO
SN  - 2045-2322
KW  - Early breast Cancer
KW  - Adjuvant radiotherapy
KW  - Accelerated partial breast irradiation
KW  - Whole breast irradiation
KW  - Health-related quality of life
KW  - QoL questionnaires
KW  - Clinical trial questionnaires
UR  - https://www.nature.com/articles/s41598-025-85342-2
N2  - lt; 0.001) scales at M0, with higher scores in the WBI arm. During follow-up, scores on symptoms scales returned to at least the baseline values. Early BC patients treated with APBI showed non-inferior short-term and late HRQoL outcomes compared to hypo-WBI. In addition to previous findings regarding toxicity, promising pain and breast symptoms results, suggest that APBI should be strongly considered as a treatment option for selected low-risk patients. Trial registration NCT06007118, August 23, 2023 (retrospectively registered).
ER  -

BURKOŇ, Petr, Iveta SELINGEROVÁ, Miroslav VRZAL, Miloš HOLÁNEK, Oldřich COUFAL, Kateřina POLÁCHOVÁ, Vera ANDRASKOVA, Sachin R JHAWAR, Pavel ŠLAMPA, Tomáš KAZDA and Marek SLÁVIK. Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial. \textit{SCIENTIFIC REPORTS}. England: NATURE PORTFOLIO, 2025, vol.~15, No~1, p.~1-12. ISSN~2045-2322. Available from: https://dx.doi.org/10.1038/s41598-025-85342-2.