Quality of life in early breast cancer patients after adjuvant
accelerated partial-breast irradiation (APBI) in randomized
trial

CSLog in Log in (EduId)

Quality of life in early breast cancer patients after adjuvant accelerated partial-breast ...

Přehled o publikaci

J 2025

Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial

BURKOŇ, Petr; Iveta SELINGEROVÁ; Miroslav VRZAL; Miloš HOLÁNEK; Oldřich COUFAL et. al.

Basic information

Original name

Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial

Authors

BURKOŇ, Petr; Iveta SELINGEROVÁ; Miroslav VRZAL; Miloš HOLÁNEK; Oldřich COUFAL; Kateřina POLÁCHOVÁ; Vera ANDRASKOVA; Sachin R JHAWAR; Pavel ŠLAMPA; Tomáš KAZDA and Marek SLÁVIK

Edition

SCIENTIFIC REPORTS, England, NATURE PORTFOLIO, 2025, 2045-2322

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Germany

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.1038/s41598-025-85342-2

UT WoS

001394278800005

EID Scopus

2-s2.0-85215102805

Keywords in English

Early breast Cancer; Adjuvant radiotherapy; Accelerated partial breast irradiation; Whole breast irradiation; Health-related quality of life; QoL questionnaires; Clinical trial questionnaires

Links

LM2023033, research and development project. LM2023049, research and development project. LX22NPO5102, research and development project. CZECRIN IV, large research infrastructures.

Changed: 26/3/2025 00:50, RNDr. Daniel Jakubík

Abstract

V originále

lt; 0.001) scales at M0, with higher scores in the WBI arm. During follow-up, scores on symptoms scales returned to at least the baseline values. Early BC patients treated with APBI showed non-inferior short-term and late HRQoL outcomes compared to hypo-WBI. In addition to previous findings regarding toxicity, promising pain and breast symptoms results, suggest that APBI should be strongly considered as a treatment option for selected low-risk patients. Trial registration NCT06007118, August 23, 2023 (retrospectively registered).

Files attached

https://is.muni.cz/publication/2474639/Quality_of_life_in_early_breast_cancer_patients_after_adjuvant_accelerated_partial-breast_irradiation__APBI__in_randomized_trial.pdf

Cite

BURKOŇ, Petr; Iveta SELINGEROVÁ; Miroslav VRZAL; Miloš HOLÁNEK; Oldřich COUFAL; Kateřina POLÁCHOVÁ; Vera ANDRASKOVA; Sachin R JHAWAR; Pavel ŠLAMPA; Tomáš KAZDA and Marek SLÁVIK. Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial. SCIENTIFIC REPORTS. England: NATURE PORTFOLIO, 2025, vol. 15, No 1, p. 1-12. ISSN 2045-2322. Available from: https://dx.doi.org/10.1038/s41598-025-85342-2.

@article{67730,
   author = {Burkoň, Petr and Selingerová, Iveta and Vrzal, Miroslav and Holánek, Miloš and Coufal, Oldřich and Poláchová, Kateřina and Andraskova, Vera and Jhawar, Sachin R and Šlampa, Pavel and Kazda, Tomáš and Slávik, Marek},
   article_location = {England},
   article_number = {1},
   doi = {http://dx.doi.org/10.1038/s41598-025-85342-2},
   keywords = {Early breast Cancer; Adjuvant radiotherapy; Accelerated partial breast irradiation; Whole breast irradiation; Health-related quality of life; QoL questionnaires; Clinical trial questionnaires},
   language = {eng},
   issn = {2045-2322},
   journal = {SCIENTIFIC REPORTS},
   title = {Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial},
   url = {https://www.nature.com/articles/s41598-025-85342-2},
   volume = {15},
   year = {2025}
}

TY  - JOUR
ID  - 67730
AU  - Burkoň, Petr - Selingerová, Iveta - Vrzal, Miroslav - Holánek, Miloš - Coufal, Oldřich - Poláchová, Kateřina - Andraskova, Vera - Jhawar, Sachin R - Šlampa, Pavel - Kazda, Tomáš - Slávik, Marek
PY  - 2025
TI  - Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial
JF  - SCIENTIFIC REPORTS
VL  - 15
IS  - 1
SP  - 1-12
EP  - 1-12
PB  - NATURE PORTFOLIO
SN  - 2045-2322
KW  - Early breast Cancer
KW  - Adjuvant radiotherapy
KW  - Accelerated partial breast irradiation
KW  - Whole breast irradiation
KW  - Health-related quality of life
KW  - QoL questionnaires
KW  - Clinical trial questionnaires
UR  - https://www.nature.com/articles/s41598-025-85342-2
N2  - lt; 0.001) scales at M0, with higher scores in the WBI arm. During follow-up, scores on symptoms scales returned to at least the baseline values. Early BC patients treated with APBI showed non-inferior short-term and late HRQoL outcomes compared to hypo-WBI. In addition to previous findings regarding toxicity, promising pain and breast symptoms results, suggest that APBI should be strongly considered as a treatment option for selected low-risk patients. Trial registration NCT06007118, August 23, 2023 (retrospectively registered).
ER  -

BURKOŇ, Petr; Iveta SELINGEROVÁ; Miroslav VRZAL; Miloš HOLÁNEK; Oldřich COUFAL; Kateřina POLÁCHOVÁ; Vera ANDRASKOVA; Sachin R JHAWAR; Pavel ŠLAMPA; Tomáš KAZDA and Marek SLÁVIK. Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial. \textit{SCIENTIFIC REPORTS}. England: NATURE PORTFOLIO, 2025, vol.~15, No~1, p.~1-12. ISSN~2045-2322. Available from: https://dx.doi.org/10.1038/s41598-025-85342-2.