J
2024
Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study
ELSHORBAGY, Amany; Alexander R M LYONS; Antonio J VALLEJO-VAZ; Christophe A T STEVENS; Kanika I DHARMAYAT et. al.
Basic information
Original name
Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study
Authors
ELSHORBAGY, Amany; Alexander R M LYONS; Antonio J VALLEJO-VAZ; Christophe A T STEVENS; Kanika I DHARMAYAT; Julia BRANDTS; Alberico L CATAPANO; Tomáš FREIBERGER; G Kees HOVINGH; Pedro MATA; Frederick J RAAL; Raul D SANTOS; Handrean SORAN; Gerald F WATTS; Marianne ABIFADEL; Carlos A AGUILAR-SALINAS; Khalid F ALHABIB; Mutaz ALKHNIFSAWI; Wael ALMAHMEED; Fahad ALNOURI; Rodrigo ALONSO; Khalid AL-RASADI; Ahmad AL-SARRAF; Tester F ASHAVAID; Maciej BANACH; Christoph J BINDER; Mafalda BOURBON; Liam R BRUNHAM; Krzysztof CHLEBUS; Pablo CORRAL; Diogo CRUZ; Kairat DAVLETOV; Olivier S DESCAMPS; Marat EZHOV; Dan GAITA; Urh GROSELJ; Mariko HARADA-SHIBA; Kirsten B HOLVEN; Meral KAYIKCIOGLU; Weerapan KHOVIDHUNKIT; Katarina LALIC; Gustavs LATKOVSKIS; Ulrich LAUFS; Evangelos LIBEROPOULOS; Marcos M LIMA-MARTINEZ; Jie LIN; Vincent MAHER; A David MARAIS; Winfried MARZ; Erkin MIRRAKHIMOV; Andre R MISEREZ; Olena MITCHENKO; Hapizah NAWAWI; Borge G NORDESTGAARD; Andrie G PANAYIOTOU; Gyorgy PARAGH; Zaneta PETRULIONIENE; Belma POJSKIC; Arman POSTADZHIYAN; Ashraf REDA; Zeljko REINER; Ximena REYES; Fouzia SADIQ; Wilson E SADOH; Heribert SCHUNKERT; Aleksandr B SHEK; Erik STROES; Ta-Chen SU; Tavintharan SUBRAMANIAM; Andrey V SUSEKOV; Myra TILNEY; Brian TOMLINSON; Truong THANH-HUONG; Alexandros D TSELEPIS; Anne TYBJAERG-HANSEN; Alejandra C VAZQUEZ; Margus VIIGIMAA; Branislav VOHNOUT; Luya WANG; Shizuya YAMASHITA; Marcello ARCA; Maurizio AVERNA and Kausik K RAY
Edition
ENDOCRINOLOGY, NEW YORK, ELSEVIER SCIENCE INC, 2024, 2213-8587
Other information
Type of outcome
Article in a journal
Country of publisher
United States of America
Confidentiality degree
is not subject to a state or trade secret
Organization
Lékařská fakulta – Repository – Repository
EID Scopus
2-s2.0-85207124416
Keywords in English
BMI; lipid-lowering medication; age; type 2 diabetes; heterozygous familial hypercholesterolaemia
Links
LX22NPO5104, research and development project.
In the original language
Background Statins are the cornerstone treatment for patients with heterozygous familial hypercholesterolaemia but research suggests it could increase the risk of type 2 diabetes in the general population. A low prevalence of type 2 diabetes was reported in some familial hypercholesterolaemia cohorts, raising the question of whether these patients are protected against type 2 diabetes. Obesity is a well known risk factor for the development of type 2 diabetes. We aimed to investigate the associations of known key determinants of type 2 diabetes with its prevalence in people with heterozygous familial hypercholesterolaemia.
Displayed: 13/12/2025 13:47