Přehled o publikaci
2024
Visualizing the effects of SORLA mutation in Alzheimer’s disease progression
SATKOVÁ, Miriam; Jan RAŠKA; Klára PLEŠINGROVÁ; Soňa CESNÁRIKOVÁ; Jiří SEDMÍK et. al.Basic information
Original name
Visualizing the effects of SORLA mutation in Alzheimer’s disease progression
Authors
SATKOVÁ, Miriam; Jan RAŠKA; Klára PLEŠINGROVÁ; Soňa CESNÁRIKOVÁ; Jiří SEDMÍK; Hana HŘÍBKOVÁ; Petr FOJTÍK and Dáša BOHAČIAKOVÁ
Edition
2024
Other information
Language
English
Type of outcome
Presentations at conferences
Country of publisher
Czech Republic
Confidentiality degree
is not subject to a state or trade secret
Organization
Lékařská fakulta – Repository – Repository
Keywords in English
SORLA mutation; Alzheimer’s disease progression
Links
LX22NPO5107, research and development project. MUNI/A/1598/2023, interní kód Repo. NU22J-08-00075, research and development project.
Changed: 26/11/2024 00:50, RNDr. Daniel Jakubík
Abstract
V originále
Aim: investigate whether pathogenic mutation Y1816C in SORL1 leads to altered APP processing and enlarged endosomes in human 2D neurons and 3D organoids in vitro.