k 2024

Mimicking brain-tumor interactions using cerebral organoids and glioblastoma spheroids to study the migration of glioblastoma cells

FEDOROVÁ, Veronika; Jana SLOVÁČKOVÁ; Kateřina AMRUZ ČERNÁ; Veronika POSPÍŠILOVÁ; Jiří SEDMÍK et. al.

Basic information

Original name

Mimicking brain-tumor interactions using cerebral organoids and glioblastoma spheroids to study the migration of glioblastoma cells

Authors

FEDOROVÁ, Veronika; Jana SLOVÁČKOVÁ; Kateřina AMRUZ ČERNÁ; Veronika POSPÍŠILOVÁ; Jiří SEDMÍK; Soňa CESNÁRIKOVÁ; Martin BARÁK; Michal HENDRYCH; Radim JANČÁLEK and Dáša BOHAČIAKOVÁ

Edition

GBM Lublaň 2023, 2024

Other information

Language

English

Type of outcome

Presentations at conferences

Country of publisher

Slovenia

Confidentiality degree

is not subject to a state or trade secret

Organization

Lékařská fakulta – Repository – Repository

Keywords in English

cerebral organoids; brain-tumor interactions; glioblastoma cells

Links

GA24-11357S, research and development project. LX22NPO5107, research and development project. MUNI/A/1598/2023, interní kód Repo. NW24-08-00157, research and development project.
Changed: 26/11/2024 00:50, RNDr. Daniel Jakubík

Abstract

In the original language

Glioblastoma IDH-wildtype is the most aggressive and lethal form of brain tumor characterized by significant heterogeneity and a poor prognosis. To advance treatment strategies, better models that replicate the in vivo behavior of glioblastoma cells are essential. Such an in vitro model can then be used to study mechanisms of therapeutic resistance and screening of new drugs against glioblastoma multiforme.

Files attached

https://is.muni.cz/publication/2454762/Mimicking_brain-tumor_interactions_using_cerebral_organoids_and_glioblastoma_spheroids_to_study_the_migration_of_glioblastoma_cells.pdf File version