Cyanine dyes in the mitochondria-targeting photodynamic and
photothermal therapy

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Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy

Přehled o publikaci

J 2024

Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy

KEJIK, Zdenek; Jan HAJDUCH; Nikita ABRAMENKO; Frederic VELLIEUX; Katerina VESELA et. al.

Basic information

Original name

Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy

Authors

Edition

COMMUNICATIONS CHEMISTRY, BERLIN, NATURE PORTFOLIO, 2024, 2399-3669

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Germany

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.1038/s42004-024-01256-6

UT WoS

001290265400001

EID Scopus

999

Keywords in English

cyanine dyes; mitochondria-targeting photodynamic therapy; photothermal therapy

Links

LM2023053, research and development project. LX22NPO5102, research and development project. LX22NPO5107, research and development project. MUNI/A/1587/2023, interní kód Repo. NU21-08-00407, research and development project.

Changed: 20/8/2024 00:50, RNDr. Daniel Jakubík

Abstract

V originále

Mitochondrial dysregulation plays a significant role in the carcinogenesis. On the other hand, its destabilization strongly represses the viability and metastatic potential of cancer cells. Photodynamic and photothermal therapies (PDT and PTT) target mitochondria effectively, providing innovative and non-invasive anticancer therapeutic modalities. Cyanine dyes, with strong mitochondrial selectivity, show significant potential in enhancing PDT and PTT. The potential and limitations of cyanine dyes for mitochondrial PDT and PTT are discussed, along with their applications in combination therapies, theranostic techniques, and optimal delivery systems. Additionally, novel approaches for sonodynamic therapy using photoactive cyanine dyes are presented, highlighting advances in cancer treatment.

Files attached

https://is.muni.cz/publication/2423697/Cyanine_dyes_in_the_mitochondria-targeting_photodynamic_and_photothermal_therapy.pdf

Cite

KEJIK, Zdenek; Jan HAJDUCH; Nikita ABRAMENKO; Frederic VELLIEUX; Katerina VESELA; Jindriska LEISCHNER FIALOVA; Kateřina PETRLÁKOVÁ; Katerina KUCNIROVA; Robert KAPLANEK; Ameneh TATAR; Marketa SKALICKOVA; Michal MASAŘÍK; Petr BABULA; Petr DYTRYCH; David HOSKOVEC; Pavel MARTASEK and Milan JAKUBEK. Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy. COMMUNICATIONS CHEMISTRY. BERLIN: NATURE PORTFOLIO, 2024, vol. 7, No 1, p. 1-39. ISSN 2399-3669. Available from: https://dx.doi.org/10.1038/s42004-024-01256-6.

@article{63047,
   author = {Kejik, Zdenek and Hajduch, Jan and Abramenko, Nikita and Vellieux, Frederic and Vesela, Katerina and Leischner Fialova, Jindriska and Petrláková, Kateřina and Kucnirova, Katerina and Kaplanek, Robert and Tatar, Ameneh and Skalickova, Marketa and Masařík, Michal and Babula, Petr and Dytrych, Petr and Hoskovec, David and Martasek, Pavel and Jakubek, Milan},
   article_location = {BERLIN},
   article_number = {1},
   doi = {http://dx.doi.org/10.1038/s42004-024-01256-6},
   keywords = {cyanine dyes; mitochondria-targeting photodynamic therapy; photothermal therapy},
   language = {eng},
   issn = {2399-3669},
   journal = {COMMUNICATIONS CHEMISTRY},
   title = {Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy},
   url = {https://www.nature.com/articles/s42004-024-01256-6},
   volume = {7},
   year = {2024}
}

TY  - JOUR
ID  - 63047
AU  - Kejik, Zdenek - Hajduch, Jan - Abramenko, Nikita - Vellieux, Frederic - Vesela, Katerina - Leischner Fialova, Jindriska - Petrláková, Kateřina - Kucnirova, Katerina - Kaplanek, Robert - Tatar, Ameneh - Skalickova, Marketa - Masařík, Michal - Babula, Petr - Dytrych, Petr - Hoskovec, David - Martasek, Pavel - Jakubek, Milan
PY  - 2024
TI  - Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy
JF  - COMMUNICATIONS CHEMISTRY
VL  - 7
IS  - 1
SP  - 1-39
EP  - 1-39
PB  - NATURE PORTFOLIO
SN  - 2399-3669
KW  - cyanine dyes
KW  - mitochondria-targeting photodynamic therapy
KW  - photothermal therapy
UR  - https://www.nature.com/articles/s42004-024-01256-6
N2  - Mitochondrial dysregulation plays a significant role in the carcinogenesis. On the other hand, its destabilization strongly represses the viability and metastatic potential of cancer cells. Photodynamic and photothermal therapies (PDT and PTT) target mitochondria effectively, providing innovative and non-invasive anticancer therapeutic modalities. Cyanine dyes, with strong mitochondrial selectivity, show significant potential in enhancing PDT and PTT. The potential and limitations of cyanine dyes for mitochondrial PDT and PTT are discussed, along with their applications in combination therapies, theranostic techniques, and optimal delivery systems. Additionally, novel approaches for sonodynamic therapy using photoactive cyanine dyes are presented, highlighting advances in cancer treatment.
ER  -

KEJIK, Zdenek; Jan HAJDUCH; Nikita ABRAMENKO; Frederic VELLIEUX; Katerina VESELA; Jindriska LEISCHNER FIALOVA; Kateřina PETRLÁKOVÁ; Katerina KUCNIROVA; Robert KAPLANEK; Ameneh TATAR; Marketa SKALICKOVA; Michal MASAŘÍK; Petr BABULA; Petr DYTRYCH; David HOSKOVEC; Pavel MARTASEK and Milan JAKUBEK. Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy. \textit{COMMUNICATIONS CHEMISTRY}. BERLIN: NATURE PORTFOLIO, 2024, vol.~7, No~1, p.~1-39. ISSN~2399-3669. Available from: https://dx.doi.org/10.1038/s42004-024-01256-6.