Child exposure to organophosphate and pyrethroid insecticides
measured in urine, wristbands, and household dust and its
implications for child health in South Africa: A panel study

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Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and ...

Přehled o publikaci

J 2024

Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health in South Africa: A panel study

VELUDO, Adriana Fernandes, Martin ROEOESLI, Mohamed Aqiel DALVIE, Petra STUCHLÍK FIŠEROVÁ, Roman PROKEŠ et. al.

Basic information

Original name

Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health in South Africa: A panel study

Authors

Edition

Environmental Epidemiology, PHILADELPHIA, Wolters Kluwer Health, 2024, 2474-7882

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

United States of America

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Přírodovědecká fakulta – Repository – Repository

DOI

http://dx.doi.org/10.1097/EE9.0000000000000282

UT WoS

001133619600001

EID Scopus

2-s2.0-85181450991

Keywords in English

Child exposure; Biomonitoring; Pesticide; Vulnerable populations; Endocrine disruptors

Links

EF17_043/0009632, research and development project. 857560, interní kód Repo. RECETOX RI II, large research infrastructures.

Changed: 26/2/2025 00:50, RNDr. Daniel Jakubík

Abstract

V originále

Background:Children in agricultural areas are exposed to organophosphate (OP) and pyrethroid (PYR) insecticides. This explorative study investigated child exposure to OPs and PYRs, comparing temporal and spatial exposure variability within and among urine, wristbands, and dust samples.Methods:During spraying season 2018, 38 South African children in two agricultural areas (Grabouw/Hex River Valley) and settings (farm/village) participated in a seven-day study. Child urine and household dust samples were collected on days 1 and 7. Children and their guardians were wearing silicone wristbands for seven days. Intraclass correlation coefficients (ICCs) evaluated temporal agreements between repeated urine and dust samples, Spearman rank correlations (Rs) evaluated the correlations among matrices, and linear mixed-effect models investigated spatial exposure predictors. A risk assessment was performed using reverse dosimetry.Results:Eighteen OPs/PYRs were targeted in urine, wristbands, and dust. Levels of chlorpyrifos in dust (ICC = 0.92) and diethylphosphate biomarker in urine (ICC = 0.42) showed strong and moderate temporal agreement between day 1 and day 7, respectively. Weak agreements were observed for all others. There was mostly a weak correlation among the three matrices (Rs = -0.12 to 0.35), except for chlorpyrifos in dust and its biomarker 3,5,6-trichloro-2-pyridinol in urine (Rs = 0.44). No differences in exposure levels between living locations were observed. However, 21% of the urine biomarker levels exceeded the health-risk threshold for OP exposure.Conclusions:Observed high short-term variability in exposure levels during spraying season highlights the need for repeated sampling. The weak correlation between the exposure matrices points to different environmental and behavioral exposure pathways. Exceeding risk thresholds for OP should be further investigated.

Files attached

https://is.muni.cz/publication/2387777/2387777.pdf

Cite

VELUDO, Adriana Fernandes, Martin ROEOESLI, Mohamed Aqiel DALVIE, Petra STUCHLÍK FIŠEROVÁ, Roman PROKEŠ, Petra PŘIBYLOVÁ, Petr ŠENK, Jiří KOHOUTEK, Mufaro MUGARI, Jana KLÁNOVÁ, Anke HUSS, Daniel Martins FIGUEIREDO, Hans MOL, Jonatan DIAS, Céline DEGRENDELE and Samuel FUHRIMANN. Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health in South Africa: A panel study. Environmental Epidemiology. PHILADELPHIA: Wolters Kluwer Health, 2024, vol. 8, No 1, p. 1-14. ISSN 2474-7882. Available from: https://dx.doi.org/10.1097/EE9.0000000000000282.

@article{60405,
   author = {Veludo, Adriana Fernandes and Roeoesli, Martin and Dalvie, Mohamed Aqiel and Stuchlík Fišerová, Petra and Prokeš, Roman and Přibylová, Petra and Šenk, Petr and Kohoutek, Jiří and Mugari, Mufaro and Klánová, Jana and Huss, Anke and Figueiredo, Daniel Martins and Mol, Hans and Dias, Jonatan and Degrendele, Céline and Fuhrimann, Samuel},
   article_location = {PHILADELPHIA},
   article_number = {1},
   doi = {http://dx.doi.org/10.1097/EE9.0000000000000282},
   keywords = {Child exposure; Biomonitoring; Pesticide; Vulnerable populations; Endocrine disruptors},
   language = {eng},
   issn = {2474-7882},
   journal = {Environmental Epidemiology},
   title = {Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health in South Africa: A panel study},
   url = {https://journals.lww.com/environepidem/fulltext/2024/02000/child_exposure_to_organophosphate_and_pyrethroid.3.aspx},
   volume = {8},
   year = {2024}
}

TY  - JOUR
ID  - 60405
AU  - Veludo, Adriana Fernandes - Roeoesli, Martin - Dalvie, Mohamed Aqiel - Stuchlík Fišerová, Petra - Prokeš, Roman - Přibylová, Petra - Šenk, Petr - Kohoutek, Jiří - Mugari, Mufaro - Klánová, Jana - Huss, Anke - Figueiredo, Daniel Martins - Mol, Hans - Dias, Jonatan - Degrendele, Céline - Fuhrimann, Samuel
PY  - 2024
TI  - Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health in South Africa: A panel study
JF  - Environmental Epidemiology
VL  - 8
IS  - 1
SP  - 1-14
EP  - 1-14
PB  - Wolters Kluwer Health
SN  - 2474-7882
KW  - Child exposure
KW  - Biomonitoring
KW  - Pesticide
KW  - Vulnerable populations
KW  - Endocrine disruptors
UR  - https://journals.lww.com/environepidem/fulltext/2024/02000/child_exposure_to_organophosphate_and_pyrethroid.3.aspx
N2  - Background:Children in agricultural areas are exposed to organophosphate (OP) and pyrethroid (PYR) insecticides. This explorative study investigated child exposure to OPs and PYRs, comparing temporal and spatial exposure variability within and among urine, wristbands, and dust samples.Methods:During spraying season 2018, 38 South African children in two agricultural areas (Grabouw/Hex River Valley) and settings (farm/village) participated in a seven-day study. Child urine and household dust samples were collected on days 1 and 7. Children and their guardians were wearing silicone wristbands for seven days. Intraclass correlation coefficients (ICCs) evaluated temporal agreements between repeated urine and dust samples, Spearman rank correlations (Rs) evaluated the correlations among matrices, and linear mixed-effect models investigated spatial exposure predictors. A risk assessment was performed using reverse dosimetry.Results:Eighteen OPs/PYRs were targeted in urine, wristbands, and dust. Levels of chlorpyrifos in dust (ICC = 0.92) and diethylphosphate biomarker in urine (ICC = 0.42) showed strong and moderate temporal agreement between day 1 and day 7, respectively. Weak agreements were observed for all others. There was mostly a weak correlation among the three matrices (Rs = -0.12 to 0.35), except for chlorpyrifos in dust and its biomarker 3,5,6-trichloro-2-pyridinol in urine (Rs = 0.44). No differences in exposure levels between living locations were observed. However, 21% of the urine biomarker levels exceeded the health-risk threshold for OP exposure.Conclusions:Observed high short-term variability in exposure levels during spraying season highlights the need for repeated sampling. The weak correlation between the exposure matrices points to different environmental and behavioral exposure pathways. Exceeding risk thresholds for OP should be further investigated.
ER  -

VELUDO, Adriana Fernandes, Martin ROEOESLI, Mohamed Aqiel DALVIE, Petra STUCHLÍK FIŠEROVÁ, Roman PROKEŠ, Petra PŘIBYLOVÁ, Petr ŠENK, Jiří KOHOUTEK, Mufaro MUGARI, Jana KLÁNOVÁ, Anke HUSS, Daniel Martins FIGUEIREDO, Hans MOL, Jonatan DIAS, Céline DEGRENDELE and Samuel FUHRIMANN. Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health in South Africa: A panel study. \textit{Environmental Epidemiology}. PHILADELPHIA: Wolters Kluwer Health, 2024, vol.~8, No~1, p.~1-14. ISSN~2474-7882. Available from: https://dx.doi.org/10.1097/EE9.0000000000000282.