J 2024

Genetic risk score in patients with the APOE2/E2 genotype as a predictor of familial dysbetalipoproteinemia

SATNY, Martin, Veronika TODOROVOVA, Tereza ALTSCHMIEDOVA, Jaroslav A HUBACEK, Lucie DLOUHA et. al.

Basic information

Original name

Genetic risk score in patients with the APOE2/E2 genotype as a predictor of familial dysbetalipoproteinemia

Authors

SATNY, Martin, Veronika TODOROVOVA, Tereza ALTSCHMIEDOVA, Jaroslav A HUBACEK, Lucie DLOUHA, Vera LANSKA, Vladimír SOŠKA, Ondřej KYSELÁK, Tomáš FREIBERGER, Martin BOBÁK and Michal VRABLIK

Edition

Journal of Clinical Lipidology, NEW YORK, ELSEVIER SCIENCE INC, 2024, 1933-2874

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

United States of America

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.1016/j.jacl.2023.11.010

UT WoS

001239945500003

EID Scopus

2-s2.0-85178638779

Keywords in English

Familial dysbetalipoproteinemia; Cardiovascular risk; Polymorphism; Genetic risk score

Links

LX22NPO5104, research and development project.
Changed: 10/7/2024 04:59, RNDr. Daniel Jakubík

Abstract

V originále

lt; 0.0005). Conclusions We identified several SNPs that are individual additive factors influencing FD development. The use of unweighted GRS2 is a simple and clinically relevant tool that further improves the prediction of FD in APOE2/E2 homozygotes with corresponding biochemical characteristics.
Displayed: 20/6/2025 01:06