Several xeric sites in the Karlovy Vary Region, mainly along railways, were surveyed for thermophilic snails of open habitats in 2019 and 2020. Two localities of Euomphalia strigella (Draparnaud, 1801), 13 localities of Monacha cartusiana (O. F. Müller, 1774) and two localities of Xerolenta obvia (Menke, 1828) were found. These three species are all new for the region. The locality of Tři Sekery (665 m a.s.l.) represents the altitudinal maximum of M. cartusiana in Czechia. Although the two sites with Xerolenta obvia were secondary; relatively high densities may suggest that these populations were established in this regions some time ago.