Concurrent weekly cisplatin and simultaneous integrated boost
intensity-modulated radiotherapy of locally advanced squamous
cell carcinoma of the head and neck

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Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of ...

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J 2022

Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of locally advanced squamous cell carcinoma of the head and neck

DUBINSKÝ, Pavol, Branislav JEREMIC, Michaela ŠVAJDOVÁ, Gabriela BARILÍKOVÁ, Pavol MATULA et. al.

Basic information

Original name

Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of locally advanced squamous cell carcinoma of the head and neck

Name in Czech

Současné podávaní cisplatiny jednou týdně a radioterapie s modulovanou intenzitou svazku s využitím simultánního integrovaného boostu při léčbě pokročilého skvamocelulárního karcinomu hlavy a krku

Authors

DUBINSKÝ, Pavol, Branislav JEREMIC, Michaela ŠVAJDOVÁ, Gabriela BARILÍKOVÁ, Pavol MATULA, Daniela NADZONOVÁ and Vladimír VOJTEK

Edition

Klinická onkologie, Praha, Česká lékařská společnost J. E. Purkyně, 2022, 0862-495X

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Czech Republic

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Organization

Lékařská fakulta – Repository – Repository

DOI

http://dx.doi.org/10.48095/ccko2022307

EID Scopus

2-s2.0-85136198228

Keywords (in Czech)

cisplatina; nádory hlavy a krku; lidský papilomavirus; karcinom orofaryngu; radioterapie

Keywords in English

cisplatin; head and neck cancer; human papillomavirus; oropharyngeal cancer; radiotherapy

Changed: 7/2/2023 04:35, RNDr. Daniel Jakubík

Abstract

V originále

lt; 0.01), DCR 100 vs. 78% (P = 0.154), PFS 80 vs. 23% (P = 0.01) and OS 80 vs. 34% (P = 0.03) for HPV positive oropharyngeal cancer (OPC) and other HPV negative LA SCCHN. Conclusion: High proportion of patients with LA SCCHN received an adequate cumulative dose of concurrent cisplatin with accelerated radiotherapy with SIB IMRT. This study demonstrated that chemoradiotherapy with weekly cisplatin resulted in favorable local control rate and survival in patients with HPV+ OPC.

Files attached

https://is.muni.cz/publication/2214997/KO_2022-04_svajdova.pdf File version

Cite

DUBINSKÝ, Pavol, Branislav JEREMIC, Michaela ŠVAJDOVÁ, Gabriela BARILÍKOVÁ, Pavol MATULA, Daniela NADZONOVÁ and Vladimír VOJTEK. Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of locally advanced squamous cell carcinoma of the head and neck. Klinická onkologie. Praha: Česká lékařská společnost J. E. Purkyně, 2022, vol. 35, No 4, p. 307-314. ISSN 0862-495X. Available from: https://dx.doi.org/10.48095/ccko2022307.

@article{51667,
   author = {Dubinský, Pavol and Jeremic, Branislav and Švajdová, Michaela and Barilíková, Gabriela and Matula, Pavol and Nadzonová, Daniela and Vojtek, Vladimír},
   article_location = {Praha},
   article_number = {4},
   doi = {http://dx.doi.org/10.48095/ccko2022307},
   keywords = {cisplatin; head and neck cancer; human papillomavirus; oropharyngeal cancer; radiotherapy},
   language = {eng},
   issn = {0862-495X},
   journal = {Klinická onkologie},
   title = {Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of locally advanced squamous cell carcinoma of the head and neck},
   url = {https://www.linkos.cz/files/klinicka-onkologie/507.pdf},
   volume = {35},
   year = {2022}
}

TY  - JOUR
ID  - 51667
AU  - Dubinský, Pavol - Jeremic, Branislav - Švajdová, Michaela - Barilíková, Gabriela - Matula, Pavol - Nadzonová, Daniela - Vojtek, Vladimír
PY  - 2022
TI  - Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of locally advanced squamous cell carcinoma of the head and neck
JF  - Klinická onkologie
VL  - 35
IS  - 4
SP  - 307-314
EP  - 307-314
PB  - Česká lékařská společnost J. E. Purkyně
SN  - 0862-495X
KW  - cisplatin
KW  - head and neck cancer
KW  - human papillomavirus
KW  - oropharyngeal cancer
KW  - radiotherapy
UR  - https://www.linkos.cz/files/klinicka-onkologie/507.pdf
N2  - lt; 0.01), DCR 100 vs. 78% (P = 0.154), PFS 80 vs. 23% (P = 0.01) and OS 80 vs. 34% (P = 0.03) for HPV positive oropharyngeal cancer (OPC) and other HPV negative LA SCCHN. Conclusion: High proportion of patients with LA SCCHN received an adequate cumulative dose of concurrent cisplatin with accelerated radiotherapy with SIB IMRT. This study demonstrated that chemoradiotherapy with weekly cisplatin resulted in favorable local control rate and survival in patients with HPV+ OPC.
ER  -

DUBINSKÝ, Pavol, Branislav JEREMIC, Michaela ŠVAJDOVÁ, Gabriela BARILÍKOVÁ, Pavol MATULA, Daniela NADZONOVÁ and Vladimír VOJTEK. Concurrent weekly cisplatin and simultaneous integrated boost intensity-modulated radiotherapy of locally advanced squamous cell carcinoma of the head and neck. \textit{Klinická onkologie}. Praha: Česká lékařská společnost J. E. Purkyně, 2022, vol.~35, No~4, p.~307-314. ISSN~0862-495X. Available from: https://dx.doi.org/10.48095/ccko2022307.