J 2022

Antiproliferative and Cytotoxic Activities of Fluorescein-A Diagnostic Angiography Dye

ŠRANKOVÁ, Mária; Aleš DVOŘÁK; Marek MARTÍNEK; Peter ŠEBEJ; Petr KLÁN et al.

Basic information

Original name

Antiproliferative and Cytotoxic Activities of Fluorescein-A Diagnostic Angiography Dye

Authors

ŠRANKOVÁ, Mária; Aleš DVOŘÁK; Marek MARTÍNEK; Peter ŠEBEJ; Petr KLÁN; Libor VÍTEK and Lucie MUCHOVÁ

Edition

International Journal of Molecular Sciences, Basel, Multidisciplinary Digital Publishing Institute, 2022, 1422-0067

Other information

Language

English

Type of outcome

Article in a journal

Country of publisher

Switzerland

Confidentiality degree

is not subject to a state or trade secret

References:

Marked to be transferred to RIV

Yes

RIV identification code

RIV/00216224:14310/22:00126023

Organization

Přírodovědecká fakulta – Repository – Repository

EID Scopus

Keywords in English

fluorescein; irradiation; singlet oxygen; carbon monoxide; viability; metabolism; proliferation

Links

EF17_043/0009632, research and development project. GA21-01799S, research and development project. GJ20-30004Y, research and development project. 857560, interní kód Repo. RECETOX RI, large research infrastructures.
Changed: 10/6/2025 00:49, RNDr. Daniel Jakubík

Abstract

In the original language

lt; 10%) as well as cell cycle arrest (decrease in the G2 phase of 18%). These observations suggest that this photochemical reaction could have important biological consequences and may account for some adverse reactions observed in fluorescein-treated patients. Additionally, the biological activities of both O-1(2) and CO might have considerable therapeutic potential, particularly in the treatment of cancer.

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