This study concerned the problem of non-professional carers in community care. Objective: The aim of the study was to describe the most significant sources of burden of non-professional caregivers of seniors with depression in the home environment. Methods: Data were collected in the form of unstructured individual interviews, where non-professional carers spoke freely about care of the seniors with depression. Results: Through analysis and categorization of individual interviews, we defined lack of time and psychological stress as the most significant sources of burden. Conclusion: The results of our survey show the need for systematic and comprehensive monitoring of the burden of non-professional caregivers of patients with depression and for elimination of the consequences of the burden of carers of this group of seniors.