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@article{17913,
   author = {Šlamborová, Irena and Zajícová, Veronika and Karpíšková, Jana and Exnar, Petr and Stibor, Ivan},
   article_number = {1},
   keywords = {methicillin-resistant Staphylococcus aureus},
   language = {eng},
   issn = {0928-4931},
   journal = {Materials Science and Engineering: C},
   title = {New type of protective hybrid and nanocomposite hybrid coatings containing silver and copper with an excellent antibacterial effect especially against MRSA},
   url = {http://www.sciencedirect.com/science/article/pii/S092849311200416X},
   volume = {33},
   year = {2013}
}

TY  - JOUR
ID  - 17913
AU  - Šlamborová, Irena - Zajícová, Veronika - Karpíšková, Jana - Exnar, Petr - Stibor, Ivan
PY  - 2013
TI  - New type of protective hybrid and nanocomposite hybrid coatings containing silver and copper with an excellent antibacterial effect especially against MRSA
JF  - Materials Science and Engineering: C
VL  - 33
IS  - 1
SP  - 265-273
EP  - 265-273
SN  - 0928-4931
KW  - methicillin-resistant Staphylococcus aureus
UR  - http://www.sciencedirect.com/science/article/pii/S092849311200416X
N2  - Epidemics spread many types of pathogenic bacterial strains, especially strains of MRSA (Methicillin-resistant Staphylococcus aureus), which are being increasingly reported in many geographical areas. This is becoming to be a serious global problem, particularly in hospitals. Not only are antibiotics proving to be increasingly ineffective but also the bacteria responsible for more than 70% of hospital-acquired bacterial infections are resistant to at least one of the drugs commonly used to treat them. In this study, hybrid coating A1 and nanocomposite hybrid coating A2 based on TMSPM (3-(trimethoxysilyl)propyl methacrylate, MMA (methyl methacrylate), TEOS (tetraethyl orthosilicate) and IPTI (titanium isopropoxide) containing silver and copper ions with or without nanoparticles of titanium dioxide were prepared by the sol–gel method. They were deposited on glass, poly(methyl methacrylate) and cotton using dip-coating or spin-coating, and then cured at 150 °C for 3 h or, in the case of poly(methyl methacrylate), at 100 °C for 4.5 h. The morphology and microstructure of these hybrid coatings were examined by SEM. The abrasion resistance was tested using a washability tester and found to depend heavily on the curing temperature. Seven types of bacterial strains were used to determine the profile of antibacterial activity, namely Escherichia coli, Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus — MRSA (CCM 4223), MRSA-2 (CCM 7112), Acinetobacter baumanii, Pseudomonas aeruginosa, and Proteus vulgaris (according to ALE-G18, CSNI). All the samples were tested by irradiating with either a UV-A or a daylight fluorescent lamp. All types of hybrid coating A1 and nanocomposite hybrid coating A2 were found to possess an excellent antibacterial effect, including against the pathogenic bacterial strains of MRSA, which present a dangerous threat on a global scale.
ER  - 

ŠLAMBOROVÁ, Irena, Veronika ZAJÍCOVÁ, Jana KARPÍŠKOVÁ, Petr EXNAR a Ivan STIBOR. New type of protective hybrid and nanocomposite hybrid coatings containing silver and copper with an excellent antibacterial effect especially against MRSA. \textit{Materials Science and Engineering: C}. 2013, roč.~33, č.~1, s.~265-273. ISSN~0928-4931.