This study presents insights into the way medical professionals write by offering an analysis of one of the basic, but often neglected, genres of written medical discourse – the case report. Specifically, it investigates structural, textual, and contextual features of online published medical case reports, adopting a genre analytic approach drawing on English for Specific Purposes research. The investigation of the most salient textual features is performed by means of the TextSTAT concordance program. For this purposes, more than a thousand case reports were collected from two open-access medical journals – Cases Journal and Journal of Medical Case Reports (approximately 2 million words). The salient textual features of these present-day reports are regarded as a consequence of the process of technologization of medical science, the advent of the Internet, and particularly the emergence of Medicine 2.0.