Flame retardants (FRs) are widely used in indoor environments to meet fire safety requirements. One understudied environment with respect to indoor chemical exposure to FRs is the maritime environment, particularly the indoor environments of cruise ships. This study presents the first comprehensive assessment of FRs in indoor dust collected from three expedition cruise ships of varying ages and refitting histories. Ten polybrominated diphenyl ethers (PBDEs), 23 alternative halogenated flame retardants (AHFRs), and 16 organophosphate esters (OPEs) were analyzed in dust from 12-16 locations per ship. OPEs, especially tris(1-chloro-2-propyl)phosphate (TCIPP), dominated the chemical profile, with concentrations reaching up to 1786 mu g g-1. Concentrations of FRs in different areas on the same ships differed greatly, sometimes by an order of magnitude. Older ships exhibited significantly higher FR levels compared to the newer vessel. Estimated daily intake (EDI) modeling indicated that ship crew members-particularly those working in heavily furnished or electronic-rich areas-may experience elevated exposures through ingestion and dermal contact. Strict performance-based fire test procedures are mandatory for all products onboard ships, but no regulations exist concerning the type of FR used or the concentrations thereof. These findings underscore the need for targeted regulation and further monitoring of chemical exposures in maritime environments, especially given the extended periods that crew members spend onboard.